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Elexacaftor

Elexacaftor ??? ???
?? ??:
2216712-66-0
???:
Elexacaftor
???(??):
VX445;Elexacaftor;Elexacaftor,VX445;lexacaftor (VX-445);Elexacaftor, 10 mM in DMSO;Elexacaftor (VX-445, WHO-11180);Elexacaftor-D3Q: What is Elexacaftor-D3 Q: What is the CAS Number of Elexacaftor-D3;N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)pyrazol-1-yl]-2-[(4S);Fibrosis,Autophagy,VX445,CFTR,VX 445,Cystic fibrosis transmembrane conductance regulator,Inhibitor,Cystic,Elexacaftor,inhibit;(S)-N-((1,3-Dimethyl-1H-pyrazol-4-yl)sulfonyl)-6-(3-(3,3,3-trifluoro-2,2-dimethylpropoxy)-1H-pyrazol-1-yl)-2-(2,2,4-trimethylpyrrolidin-1-yl)nicotinamide
CBNumber:
CB94848184
???:
C26H34F3N7O4S
??? ??:
597.65
MOL ??:
2216712-66-0.mol

Elexacaftor ??

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206 - 208°C
??
1.38±0.1 g/cm3(Predicted)
?? ??
-20°C Freezer, Under inert atmosphere
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?????(?? ???), DMSO(?? ???), ???(?? ???)
?? ?? (pKa)
3.80±0.10(Predicted)
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  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P280 ????/???/???/?????? ?????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P321 (…) ??? ???.
P330 ?? ?????.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P362 ??? ??? ?? ?? ?? ?????
P501 ...? ??? / ??? ?? ???.
NFPA 704
0
2 0

Elexacaftor C??? ??, ??, ??

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Elexacaftor medication used in those that have cystic fibrosis with a f508del mutation.

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Elexacaftor ?? ??:

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