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DiAzKs

DiAzKs ??? ???
?? ??:
1253643-88-7
???:
DiAzKs
???(??):
DiAzKs;H-L-Photo-lysine;Cross-Linking-Amino-Acid / DiAzK;N6-[[2-(3-Methyl-3H-diazirin-3-yl)ethoxy]carbonyl]-L-lysine;L-Lysine, N6-[[2-(3-methyl-3H-diazirin-3-yl)ethoxy]carbonyl]-
CBNumber:
CB94656145
???:
C11H20N4O4
??? ??:
272.3
MOL ??:
1253643-88-7.mol

DiAzKs ??

??
1.39±0.1 g/cm3(Predicted)
???
Soluble to 10 mM in water with gentle warming and to 100 mM in 1eq. HCl
?? ?? (pKa)
2.53±0.24(Predicted)
??? ??
Solid
??
White to yellow

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DiAzKs C??? ??, ??, ??

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H-L-Photo-lysine HCl is a diazirine-containing lysine amino acid and multifunctional probe building blocks. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (~360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An Fmoc-protected version is also available as 907383.

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