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5-Chloro-6-hydroxynicotinic Acid

5-Chloro-6-hydroxynicotinic Acid ??? ???
?? ??:
54127-63-8
???:
5-Chloro-6-hydroxynicotinic Acid
???(??):
TIMTEC-BB SBB003814;Avatrombopag Impurity 53;Nicotinic Acid Impurity 16;oro-6-hydroxynicotinic Acid;5-CHLORO-6-HYDROXYNICOTINIC ACID;5-Chloro-6-hydroxynicotinicacid,98%;5-Chloro-6-hydroxynicotinic acid 98%;5-Chloro-6-hydroxynicotinic Acid >5-CHLORO-6-HYDROXY-3-PYRIDINECARBOXYLIC ACID;3-CHLORO-2-HYDROXYPYRIDINE-5-CARBOXYLIC ACID
CBNumber:
CB9399994
???:
C6H4ClNO3
??? ??:
173.55
MOL ??:
54127-63-8.mol

5-Chloro-6-hydroxynicotinic Acid ??

???
≥300 °C(lit.)
?? ?
334.6±42.0 °C(Predicted)
??
1.4914 (rough estimate)
???
1.5810 (estimate)
?? ??
Sealed in dry,Room Temperature
??? ??
powder to crystal
?? ?? (pKa)
3.38±0.50(Predicted)
??
White to Light yellow to Light orange
CAS ??????
54127-63-8(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi,Xn
?? ???? ?? 36/37/38-20/21/22
????? 26-37/39-36
WGK ?? 3
?? ?? ?? Irritant
HS ?? 2933399990
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P405 ???? ?????.
NFPA 704
0
2 0

5-Chloro-6-hydroxynicotinic Acid C??? ??, ??, ??

??? ??

white to beige fine crystalline powder

?? ??

[1] Rui C. Santos. “Energetics and Structure of Hydroxynicotinic Acids. Crystal Structures of 2-, 4-, 6-Hydroxynicotinic and 5-Chloro-6-hydroxynicotinic Acids.” The Journal of Physical Chemistry B 113 43 (2009): 14291–14309.

5-Chloro-6-hydroxynicotinic Acid ?? ?? ? ???

???

?? ??


5-Chloro-6-hydroxynicotinic Acid ?? ??

???( 206)?? ??
??? ?? ??? ?? ?? ? ??
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5-Chloro-6-hydroxynicotinic Acid ?? ??:

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