ChemicalBook >?? ???? >???????3
???????3
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???????3 ??
- ?? ?
- 383.5±37.0 °C(Predicted)
- ??
- 1.150±0.06 g/cm3 (20 ºC 760 Torr)
- ?? ??
- -20°C
- ???
- ?? DMSO ?? DMF? ? 20mM? ?????. ?? ???? -20°C? ?????.
- ?? ?? (pKa)
- 10.12±0.46(Predicted)
- ??? ??
- ??
- ??
- ???
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| ????? | 22-24/25 | ||
|---|---|---|---|
| WGK ?? | 3 |
???????3 C??? ??, ??, ??
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N-Boc-L-aspartic acid 4-methyl ester fluoromethyl ketone is used as a novel Boc-D(OMe)-FMK inhibitor synthesized using proprietary technology and irreversibly binds to activated caspases to block apoptosis. It is useful for in vitro and in vivo applications.Biochem/physiol Actions
Boc-Asp(OMe)-fluoromethyl ketone (Boc-D-fmk) permits cell permeability. It is a caspase inhibitor and suppresses apoptosis induced by various kinds of stimuli. Boc-D-fmk poorly inhibits caspases-2, -5, -6 and -10.???????3 ?? ?? ? ???
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???????3 ?? ??
???( 59)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32965 | 60 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 8497 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32161 | 58 |
| BOC Sciences | 16314854226; +16314854226 |
inquiry@bocsci.com | United States | 19741 | 58 |
| TargetMol Chemicals Inc. | |
support@targetmol.com | United States | 38631 | 58 |
| Shanxi Tihondan Pharmaceutical Technology Co., Ltd | +8618235132063 |
sales@tihondan.com | China | 3741 | 58 |
| Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 |
sales@bicbiotech.com | China | 5994 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57505 | 58 |
| Hangzhou Baige Pharmaceutical Technology Co. , Ltd. | 0571-85350119 15888826472 |
15888826472@163.com | China | 2729 | 58 |
| Hangzhou Beiputai Biopharmaceutical Co., Ltd | 0571-85350119 15888826472 |
bptsales@163.com | China | 3851 | 58 |
???????3 ?? ??:
??????? ?2? ????? ??(2,2,6,6-?????-3,5-???????) ???? ????????? ???(II) ????????? ?????? ??????? ?? ?? ?????????
SALCOMINE
Tris(2,4-pentanedionato)chroMiuM(III)
Tosylmethyl isocyanide
Benzyl isocyanide
DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
TERT-BUTYL ISOCYANIDE
METHYL ISOCYANOACETATE
N-BUTYLISOCYANIDE
TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)
PHENYLSELENOL
Ethyl isocyanoacetate