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Niraparib metabolite M1

Niraparib metabolite M1 ??? ???
?? ??:
1476777-06-6
???:
Niraparib metabolite M1
???(??):
Niraparib Impurity 2;Niraparib Impurity 1;Nirapanib Impurity 1;Niraparib Impurity 49;Niraparib Impurity 15;Niraparib metabolite M1;Niraparib Carboxylic Acid;M1 metabolite of niraparib;Niraparib Metabolite M1-D4;Niraparib Metabolite M1 hydrochloride
CBNumber:
CB93155067
???:
C19H19N3O2
??? ??:
321.37
MOL ??:
1476777-06-6.mol

Niraparib metabolite M1 ??

?? ?
442.0±45.0 °C(Predicted)
??
1.34±0.1 g/cm3(Predicted)
?? ??
Store at -20°C
???
DMSO : ≥ 100 mg/mL (311.17 mM)
??? ??
Solid
?? ?? (pKa)
-2.18±0.30(Predicted)
??
Light brown to brown

??

Niraparib metabolite M1 C??? ??, ??, ??

??

Niraparib Carboxylic Acid is an impurity of Niraparib (N481400), a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.

Niraparib metabolite M1 ?? ?? ? ???

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Niraparib metabolite M1 ?? ??

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Niraparib metabolite M1 ?? ??:

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