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LY-2922470

LY-2922470 ??? ???
?? ??:
1423018-12-5
???:
LY-2922470
???(??):
LY2922470;LY-2922470;LY 2922470,LY-2922470,LY2922470,Free Fatty Acid Receptor,inhibit,Inhibitor,FFAR;(3S)-3-[4-[[5-[(8-methoxy-3,4-dihydro-2H-quinolin-1-yl)methyl]-2-thienyl]methoxy]phenyl]hex-4-ynoic acid;(S)-3-(4-((5-((8-METHOXY-3,4-DIHYDROQUINOLIN-1(2H)-YL)METHYL)THIOPHEN-2-YL)METHOXY)PHENYL)HEX-4-YNOIC ACID;Benzenepropanoic acid, 4-[[5-[(3,4-dihydro-8-methoxy-1(2H)-quinolinyl)methyl]-2-thienyl]methoxy]-β-1-propyn-1-yl-, (βS)-
CBNumber:
CB93133360
???:
C28H29NO4S
??? ??:
475.6
MOL ??:
1423018-12-5.mol

LY-2922470 ??

?? ?
689.1±55.0 °C(Predicted)
??
1.247±0.06 g/cm3(Predicted)
?? ??
Store at -20°C
???
DMSO: ≥ 125 mg/mL (262.83 mM)
??? ??
Solid
?? ?? (pKa)
4.19±0.10(Predicted)
??
Off-white to light yellow

??

LY-2922470 C??? ??, ??, ??

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LY 2922470, has demonstrated potent, efficacious and durable dose dependent reduction in glucose levels along with significant increases in insulin and GLP-1 secretion during preclinical testing. It’s a novel, potent and Selective GPR40 Agonists for the treatment of type 2 Diabetes Mellitus.

LY-2922470 ?? ?? ? ???

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LY-2922470 ?? ??

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