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WZ4003

WZ4003 ??? ???
?? ??:
1214265-58-3
???:
WZ4003
???(??):
WZ4003;CS-1174;WZ 4003;WZ4003;N-[3-[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]propanamide;N-[3-[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]oxy]phenyl]propanamide;N-(3-((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)oxy)phenyl)propionamide;Propanamide, N-[3-[[5-chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]oxy]phenyl]-
CBNumber:
CB92707353
???:
C25H29ClN6O3
??? ??:
496.99
MOL ??:
1214265-58-3.mol
MSDS ??:
SDS

WZ4003 ??

??
1.303±0.06 g/cm3(Predicted)
?? ??
-20°C
???
insoluble in H2O; ≥2.68 mg/mL in EtOH with gentle warming and ultrasonic; ≥7.85 mg/mL in DMSO with gentle warming
?? ?? (pKa)
14.27±0.70(Predicted)
??? ??
??
??
???? ????
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  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
??????:

WZ4003 C??? ??, ??, ??

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WZ4003 is a highly specific protein kinase inhibitor of NUAK kinases.

Biochem/physiol Actions

WZ4003 helps to repress the migration of cells. It also prevents cell proliferation.

WZ4003 ?? ?? ? ???

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WZ4003 ?? ??

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WZ4003 ?? ??:

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