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??60-6583

??60-6583
??60-6583 ??? ???
?? ??:
910487-58-0
???:
??60-6583
???(??):
??60-6583
???:
BAY 60-6583
???(??):
BAY 60-6583;BAY 606583,BAY 60 6583;BAY 60-6583, 10 mM in DMSO;2-((6-Amino-3,5-dicyano-4-(4-(cyclopropylmethoxy)phenyl)pyridin-2-yl)thio)acetamide;2-[[6-Amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide;Acetamide, 2-[[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-;2-((6-Amino-3,5-dicyano-4-(4-(cyclopropylmethoxy)phenyl)pyridin-2-yl)thio)acetamide , BAY 60-6583
CBNumber:
CB92695645
???:
C19H17N5O2S
??? ??:
379.44
MOL ??:
910487-58-0.mol
MSDS ??:
SDS

??60-6583 ??

?? ?
684.8±55.0 °C(Predicted)
??
1.43±0.1 g/cm3(Predicted)
?? ??
2-8°C
???
DMSO? ???
??? ??
??
?? ?? (pKa)
14.98±0.40(Predicted)
??
???? ????
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
WGK ?? 3
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 ??? ???? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H332 ???? ??? ?? ?? ?? ?? ?? 4 ?? GHS hazard pictograms P261, P271, P304+P340, P312
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P302+P352 ??? ??? ??? ?? ????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P330 ?? ?????.
P363 ?? ??? ??? ??? ?????.
P501 ...? ??? / ??? ?? ???.

??60-6583 C??? ??, ??, ??

??

BAY 60-6583 is a potent and selective adenosine A2B receptor agonist. BAY 60-6583 shows protective effects against ischemia in both the heart and kidney in animal models. BAY 60-6583 is also a useful therapeutic drug in the treatment of acute lung injury.

??

ChEBI: A member of the class of cyanopyridines that is 6-amino-3,5-dicyano-4-(4-hydroxyphenyl)-2-sulfanylpyridine in which the hydroxy and sulfanyl hydrogens are replaced by cyclopropylmethyl and carboxamidomethyl groups respectively.

??60-6583 ?? ?? ? ???

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??60-6583 ?? ??

???( 51)?? ??
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