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??????F

??????F
??????F ??? ???
?? ??:
163768-50-1
???:
??????F
???(??):
??????F
???:
Auristatin F
???(??):
CS-1370;Auristatin F;Auristantin F;Auristatin F (AF);Auristatin F TFA Salt;microtubule,VDA,cytotoxin,ADC Payload,Conjugate,vascular,Auristatin F,damaging,ADC Cytotoxin,inhibit,Microtubule/Tubulin,inhibitor,agent;L-Phenylalanine, N,N-dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-;N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide;(S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(Dimethylamino)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic acid
CBNumber:
CB92667493
???:
C40H67N5O8
??? ??:
746
MOL ??:
163768-50-1.mol

??????F ??

???
>140°C (dec.)
?? ?
894.4±65.0 °C(Predicted)
??
1.112±0.06 g/cm3(Predicted)
?? ??
Hygroscopic, -20°C Freezer, Under inert atmosphere
???
DMSO(?? ???), ???(?? ???, ??)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
3.56±0.10(Predicted)
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