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Mahanimbine

Mahanimbine ??? ???
?? ??:
21104-28-9
???:
Mahanimbine
???(??):
Mahanimbin;Mahanimbine;Mahanimbine-RM;(+)-Mahanimbine;(+)-3,11-Dihydro-3,5-dimethyl-3-(4-methyl-3-penten-1-yl)pyrano[3,2-a]carbazole;Pyrano[3,2-a]carbazole, 3,11-dihydro-3,5-dimethyl-3-(4-methyl-3-penten-1-yl)-, (3S)-
CBNumber:
CB92056338
???:
C23H25NO
??? ??:
331.45
MOL ??:
21104-28-9.mol

Mahanimbine ??

???
94-95 °C
?? ?
502.6±39.0 °C(Predicted)
??
1.109
???
DMSO: 10 mM
?? ?? (pKa)
17.31±0.40(Predicted)
???
???
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
?? ???? ?? 53
WGK ?? 3
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H413 ??? ??? ?? ????? ??? ??? ?? ?? ????? ?? - ?? ?? 4
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P273 ???? ???? ???.
P280 ????/???/???/?????? ?????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

Mahanimbine C??? ??, ??, ??

??

The leaves of Murraya koenigii Spreng. also furnish this crystalline alkaloid which is dextrorotatory with [α]D + 52° (CHCI3). The ultraviolet spectrum exhibits several absorption maxima occurring at 227, 288,300,315,328,343 and 357 mil. It furnishes a crystalline picrate as pale yellow needles, m.p. 142°C and on catalytic reduction gives the dihydro derivative, m.p. 101°C and finally the tetrahydro compound, m.p. 108°C. Spectroscopic and chemical data support the structure given above.

?? ??

Chakraborty, Das, Bose., Sci. Cult. (Calcutta), 32, 83 (1966) Structure: Narasimhan, Paradkar, Chitguppi., Tetrahedron Lett., 5501 (1968)

Mahanimbine ?? ?? ? ???

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Mahanimbine ?? ??

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Mahanimbine ?? ??:

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