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2013-12-9
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D(-)-Norvaline
???(??):
(R)-2-AMINOPENTANOIC ACID;D-NORVALINE;H-D-NVA-OH;D-Nval;D-Nva-OH;D-NorvaL;D-NVal-OH;D-n-valine;H-D-APE(2)-OH;H-D-NORVALINE
CBNumber:
CB8462680
???:
C5H11NO2
??? ??:
117.15
MOL ??:
2013-12-9.mol

??? ??

???
>300 °C(lit.)
??
-24 º (c=5, 5N HCl)
?? ?
222.9±23.0 °C(Predicted)
??
1.2000 (estimate)
???
-25 ° (C=10, 6mol/L HCl)
?? ??
Store at RT.
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??
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?? ?? (pKa)
2.54±0.20(Predicted)
??
???? ?????
optical activity
[α]20/D 24°, c = 10 in 5 M HCl
???
??
Merck
14,6716
BRN
1721161
CAS ??????
2013-12-9(CAS DataBase Reference)
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  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 20/21/22-36/37/38
????? 22-24/25-37/39-26
WGK ?? 3
HS ?? 29224919
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P337+P313 ?? ?? ??? ???? ???? ??· ??? ????.
NFPA 704
1
0 0

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white to off-white crystals or crystalline powder

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D-Norvaline is used as a catalyst in the enantioselective α-bromination of carbonyl and 1,3-dicarbonyl compounds. D-Norvaline is also incorporated into jadomycins (a group of compounds that are widely used as antibiotics), ultimately producing compounds that have potential antiproliferative/anti-cancer properties.

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