ChemicalBook >?? ???? >3-Chloro-4-fluoro-5-nitro-benzoic acid
3-Chloro-4-fluoro-5-nitro-benzoic acid
|
|
3-Chloro-4-fluoro-5-nitro-benzoic acid ??
- ?? ?
- 369.0±42.0 °C(Predicted)
- ??
- 1.689±0.06 g/cm3(Predicted)
- ?? ?? (pKa)
- 3.17±0.10(Predicted)
- InChI
- InChI=1S/C7H3ClFNO4/c8-4-1-3(7(11)12)2-5(6(4)9)10(13)14/h1-2H,(H,11,12)
- InChIKey
- FSXCNZDIJKLGGU-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC([N+]([O-])=O)=C(F)C(Cl)=C1
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ????(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ?? ?: | Warning | |||||||||||||||||||||||||||||||||||
| ??·?? ??: |
|
|||||||||||||||||||||||||||||||||||
| ??????: |
|
3-Chloro-4-fluoro-5-nitro-benzoic acid C??? ??, ??, ??
Synthesis
A round bottom flask was charged with 3-chloro-4-fluorobenzoic acid (2.50 g, 14.32 mmol) and sulfuric acid (10 ml), and nitric acid (0.91 mL, 21.48 mmol) was added slowly. The reaction mixture was stirred at rt for 30 min and then heated to 100 °C and stirred at that temperature for 2h. After cooling to room temperature, the reaction mixture was poured into ice cold water and the precipitated solids were collected by filtration and washed with water and dried to afford 3-Chloro-4-fluoro-5-nitro-benzoic acid (2.44 g, 78%).3-Chloro-4-fluoro-5-nitro-benzoic acid ?? ?? ? ???
???
?? ??
3-Chloro-4-fluoro-5-nitro-benzoic acid ?? ??
???( 22)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Shanghai Qianyi New Material Co., Ltd. | +8618083322317 |
3391883138@qq.com | China | 878 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 |
sale04@alfachem.cn | China | 11853 | 58 |
| Golden Pharma Co., Limited | +undefined18958062155 |
sales@zjgoldpharm.com | China | 5899 | 58 |
| Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 131957 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 13681763483 |
product02@bidepharm.com | China | 41457 | 60 |
| SuZhou ShiYa Biopharmaceuticals, Inc. | 0512-0512-52358471 17715136450 |
sales@shiyabiopharm.com | China | 12149 | 58 |
| Jiangsu aikang biomedical research and development co., LTD | 025-66110311 13155353615 |
qzhang@aikonchem.com | China | 15526 | 58 |
| Henan Alpha Chemical Co., Ltd. | 0371-0371-55055611 18137792234 |
3002694073@qq.com | China | 10530 | 58 |
| Nanchang Lanna Chemical Co., Ltd. | 15079032866 |
1701267076@qq.com | China | 118 | 58 |
| Changzhou Yinghao Technology Development Co., Ltd | 15151934985 |
sales@yingsapharm.com | China | 4337 | 58 |