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Pemetrexed Disodium Heptahydrate

Pemetrexed Disodium Heptahydrate ??? ???
?? ??:
357166-29-1
???:
Pemetrexed Disodium Heptahydrate
???(??):
CS-248;Pemetrexed disodium(7HO);7-dihydro-4-oxo-3H-pyrrolo[2;PeMetrexed disodiuM 7-hydrate;Pemetrexed Disodium (1500659);Pemetrexed disodium hepthydrate;Pemetrexed (sodium salt hydrate);Pemetrexed for system suitability;Pemetrexed disodium 7 hydrate (CEP);Pemetrexed disodium heptahydrate CRS
CBNumber:
CB82509918
???:
C20H24N5NaO7
??? ??:
469.43
MOL ??:
357166-29-1.mol
MSDS ??:
SDS

Pemetrexed Disodium Heptahydrate ??

?? ??
2-8°C
???
H2O: ???30mg/mL, ??
??? ??
??
??
???? ????
???
??? ?? 1? ?? ??????. ??? ??? -20°?? ?? 31?? ?? ??? ? ????.
InChIKey
AEZRDYKQLPDYEH-YTCXBBKHNA-N
SMILES
C(C1=CNC2NC(N)=NC(=O)C1=2)CC1C=CC(C(=O)N[C@H](C(=O)O)CCC(=O)O)=CC=1.[NaH].O |&1:20,r|
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????? 24/25
WGK ?? 3
HS ?? 29335990
????(GHS): GHS hazard pictogramsGHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H341 ???? ??? ??? ??? ??? (????? ???? ????? ???? ???? ???? ??? ?? ????? ??? ???? ??) ???? ???? ?? ?? 2 ?? P201,P202, P281, P308+P313, P405,P501
H372 ??? ?? ?? ???? ??(??, ??? ?? ??? ?? ??? ??)? ??? ??? ?? ???? ?? - ?? ?? ?? 1 ?? GHS hazard pictograms P260, P264, P270, P314, P501
??????:
P202 ?? ?? ?? ??? ?? ???? ??? ???? ???.
P260 ??·?·??·???·??·...·????? ???? ???.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P308+P313 ?? ?? ??? ???? ???? ??· ??? ????.
NFPA 704
0
2 0

Pemetrexed Disodium Heptahydrate C??? ??, ??, ??

?? ??

Pemetrexed Disodium Heptahydrate secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pemetrexed is an anionic anticancer drug with a narrow therapeutic index. As a folate anti metabolite, it acts as an inhibitor of thymidylate synthase. It can act effectively against a broad-spectrum of solid tumors such as non-small-cell lung and breast cancers in clinical trials. It is also effective against both dihydrofolate reductase and glycinamide ribonucleotide formyl transferase.

Biochem/physiol Actions

Pemetrexed exhibits its activity against several tumors such as colorectal, breast, gastric, pancreatic, and cervical cancer. It acts as a substrate for multidrug resistance protein transporters.

Pemetrexed Disodium Heptahydrate ?? ?? ? ???

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?? ??


Pemetrexed Disodium Heptahydrate ?? ??

???( 240)?? ??
??? ?? ??? ?? ?? ? ??
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Pemetrexed Disodium Heptahydrate ?? ??:

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