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?? ???? >3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE
3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE
3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE ??? ???
?? ??:
195199-95-2
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3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE
???(??):
SB 258719;SB-258719 >=98% (HPLC);SB 258719 HYDROCHLORIDE;SB 258719, 10 mM in DMSO;Benzenesulfonamide, N,3-dimethyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-;3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE;5-HT Receptor,5-hydroxytryptamine Receptor,agonism,SB258719,Inhibitor,inverse,hydrochloride,partial,SB 258719,SB-258719,apparent,selective,inhibit,Serotonin Receptor,affinity
CBNumber:
CB82453437
???:
C18H30N2O2S
??? ??:
338.51
MOL ??:
195199-95-2.mol
3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE ??
?? ?
463.6±55.0 °C(Predicted)
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1.075±0.06 g/cm3(Predicted)
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Desiccate at RT
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DMSO: 250 mg/mL (738.53 mM)
?? ?? (pKa)
9.36±0.10(Predicted)
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Liquid
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Light yellow to yellow
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3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE C??? ??, ??, ??
???? ??
Selective 5-HT 7 receptor antagonist that displays > 100-fold selectivity over a range of other receptors. Reverses the hypothermic effect of 5-CT in mice following i.p. administration.
3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE ?? ?? ? ???
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3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE ?? ??
???( 18)?? ??
China 13
United Kingdom 1
United States 4
Global 18
3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE ?? ??: