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3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE

3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE ??? ???
?? ??:
195199-95-2
???:
3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE
???(??):
SB 258719;SB-258719 >=98% (HPLC);SB 258719 HYDROCHLORIDE;SB 258719, 10 mM in DMSO;Benzenesulfonamide, N,3-dimethyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-;3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE;5-HT Receptor,5-hydroxytryptamine Receptor,agonism,SB258719,Inhibitor,inverse,hydrochloride,partial,SB 258719,SB-258719,apparent,selective,inhibit,Serotonin Receptor,affinity
CBNumber:
CB82453437
???:
C18H30N2O2S
??? ??:
338.51
MOL ??:
195199-95-2.mol

3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE ??

?? ?
463.6±55.0 °C(Predicted)
??
1.075±0.06 g/cm3(Predicted)
?? ??
Desiccate at RT
???
DMSO: 250 mg/mL (738.53 mM)
?? ?? (pKa)
9.36±0.10(Predicted)
??? ??
Liquid
??
Light yellow to yellow

??

3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE C??? ??, ??, ??

???? ??

Selective 5-HT 7 receptor antagonist that displays > 100-fold selectivity over a range of other receptors. Reverses the hypothermic effect of 5-CT in mice following i.p. administration.

3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE ?? ?? ? ???

???

?? ??


3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE ?? ??

???( 18)?? ??
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3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE ?? ??:

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