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5-(Aminomethyl)-2-fluorobenzonitrile

5-(Aminomethyl)-2-fluorobenzonitrile ??? ???
?? ??:
368426-86-2
???:
5-(Aminomethyl)-2-fluorobenzonitrile
???(??):
3-Cyano-4-fluorobenzylamine;5-(aminomethyl)-2-fluorobenzonitrile;Benzonitrile, 5-(aminomethyl)-2-fluoro-;3-Cyano-4-fluorobenzylamine hydrochloride;Benzonitrile, 5-(aminomethyl)-2-fluoro- (9CI);5-(AMINOMETHYL)-2-FLUOROBENZONITRILE(WX191678)
CBNumber:
CB7854983
???:
C8H7FN2
??? ??:
150.15
MOL ??:
368426-86-2.mol
MSDS ??:
SDS

5-(Aminomethyl)-2-fluorobenzonitrile ??

?? ?
264.2°C
??
1.20
???
114°C
?? ??
under inert gas (nitrogen or Argon) at 2–8 °C
?? ?? (pKa)
8.51±0.10(Predicted)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
HS ?? 2926907090
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P321 (…) ??? ???.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P362 ??? ??? ?? ?? ?? ?????

5-(Aminomethyl)-2-fluorobenzonitrile C??? ??, ??, ??

??

5-Aminomethyl-2-fluorobenzonitrile is used in the synthesis thrombin inhibitors containing P3-heterocycles with P1-bicyclic arginine surrogates.

5-(Aminomethyl)-2-fluorobenzonitrile ?? ?? ? ???

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5-(Aminomethyl)-2-fluorobenzonitrile ?? ??

???( 43)?? ??
??? ?? ??? ?? ?? ? ??
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5-(Aminomethyl)-2-fluorobenzonitrile ?? ??:

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