ChemicalBook >?? ???? >?? ???>?? ??? ???>(S)-(+)-Glycidyl Phthalimide

(S)-(+)-Glycidyl Phthalimide

(S)-(+)-Glycidyl Phthalimide ??? ???

?? ??:: 161596-47-0

???:: (S)-(+)-Glycidyl Phthalimide

???(??):: PHTHAL;(S)-2-OXIRANYLMETHYL-ISOINDOLE-1,3-DIONE;S-Glycidyl Phthalamide;(S)-N-Glycidylphthalimide;2-[[(2S)-oxiran-2-yl]methyl]isoindoline-1,3-dione;2-[(2S)-ox;(S)-(+)-GL;2-Amino-8-picoline;Linezolid EPP Impurity;Rivaroxaban Impurity R

CBNumber:: CB7273483

???:: C11H9NO3

??? ??:: 203.19

MOL ??:: 161596-47-0.mol

MSDS ??:: SDS

?? ?? 650

(S)-(+)-Glycidyl Phthalimide ??

???: 102 °C

?? ?: 347.4±15.0 °C(Predicted)

??: 1.446±0.06 g/cm3(Predicted)

???: 0.001-2.17Pa at 25-90.25℃

???: 10 ° (C=2.2, CHCl3)

?? ??: under inert gas (nitrogen or Argon) at 2-8°C

???: ?????(?? ???), ???????(?? ???)

?? ?? (pKa): -2.24±0.20(Predicted)

??? ??: ??

??? ??: ??? ??

??: ???

InChI: InChI=1S/C11H9NO3/c13-10-8-3-1-2-4-9(8)11(14)12(10)5-7-6-15-7/h1-4,7H,5-6H2/t7-/m0/s1

InChIKey: DUILGEYLVHGSEE-ZETCQYMHSA-N

SMILES: C1(=O)C2=C(C=CC=C2)C(=O)N1C[C@H]1CO1

LogP: 1.2 at 40℃

?? ? ?? ??
?? ? ???? ?? (GHS)

??? ??	Xi
?? ???? ??	41
?????	26-39
WGK ??	2
HS ??	29252900

????(GHS):

?? ?:

Danger

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	?? ??	P- ??
H318	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 1	??		P280, P305+P351+P338, P310
H341	???? ??? ??? ??? ??? (????? ???? ????? ???? ???? ???? ??? ?? ????? ??? ???? ??)	???? ???? ??	?? 2	??		P201,P202, P281, P308+P313, P405,P501

??????:

P201	?? ? ?? ???? ?????.
P202	?? ?? ?? ??? ?? ???? ??? ???? ???.
P280	????/???/???/?????? ?????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P308+P313	?? ?? ??? ???? ???? ??· ??? ????.
P405	???? ?????.
P501	...? ??? / ??? ?? ???.

NFPA 704

	0
2		0

(S)-(+)-Glycidyl Phthalimide C??? ??, ??, ??

??? ??

White powder

??

(S)-(+)-Glycidyl Phthalimide is a phthalimide derivative used as an intermediate in the preparation of the antibiotic Linezolid (L466500). It is also a key intermediate of rivaroxaban.

(S)-(+)-Glycidyl Phthalimide ?? ?? ? ???

???

?? ??

2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-Morpho linyl)phenyl]aMino]propyl]-1H-isoindole-1 ,3(2H)-dione

(S)-(+)-Glycidyl Phthalimide ?? ??

???( 650)?? ??

???	??	???	??	?? ?	??
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(S)-(+)-Glycidyl Phthalimide ?? ??:

1,2-???????? (S)-????????? ????? N-(Chloromethyl)phthalimide 4-(4-AMINOPHENYL)MORPHOLIN-3-ONE AcetaMide, N-[[(5S)-2-oxo-3-[4-(3-oxo-4-Morpholinyl)phenyl]-5-oxazolidinyl]Methyl]- Rivaroxaban iMpurity 5 Rivaroxaban Impurity 43 Rivaroxaban Impurity 34 4-(4-NITROPHENYL)MORPHOLIN-3-ONE 4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)aMino)phenyl]Morpholin-3-one (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one.HCl 5-CHLOROTHIOPHENE-2-CARBONYL CHLORIDE Ethyl (R)-(-)-4-cyano-3-hydroxybutyate 3-MORPHOLINONE, 4-[4-[(5S)-5-(AMINOMETHYL)-2-OXO-3-OXAZOLIDINYL]PHENYL]- 5-Chloro-2-thiophenecarboxylic Acid m-(Trifluoromethyl)phenylacetic acid 2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-Morpho linyl)phenyl]aMino]propyl]-1H-isoindole-1 ,3(2H)-dione

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