??? ????????
|
|
??? ???????? ??
- ???
- 174-175°C
- ?? ?
- 213.8±23.0 °C(Predicted)
- ??
- 1.142 (estimate)
- ???
- 1.5800 (estimate)
- ???
- ???? ???
- ??? ??
- powder to crystal
- ?? ?? (pKa)
- 12.20±0.70(Predicted)
- ??
- ???? ?? ???
- InChIKey
- FQUDPIIGGVBZEQ-UHFFFAOYSA-N
- CAS ??????
- 1752-30-3(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ?? ???? ?? | 21-25-26 | ||
|---|---|---|---|
| ????? | 22-28-36/37/39 | ||
| ????(UN No.) | 2811 | ||
| RTECS ?? | AL7350000 | ||
| HS ?? | 2930.90.9250 | ||
| ?? ?? | 6.1 | ||
| ???? | I | ||
| ?? ?? ??? | 1752-30-3(Hazardous Substances Data) | ||
| ?? | mouse,LD50,intraperitoneal,23mg/kg (23mg/kg),BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD,Journal of Pharmacology and Experimental Therapeutics. Vol. 122, Pg. 110, 1958. | ||
| ???? ?? | KE-05-0003 | ||
| ?????? ??? | 98-1-478 | ||
| ?? ? ???? | ????: ????; ???(??)????: ??? ???????? ? ?? 1% ?? ??? ??? |
??? ???????? C??? ??, ??, ??
??? ??
Acetone thiosemicarbazide is a white to yellow crystalline solid?? ??
Solid.?? ???
Acetone thiosemicarbazone may form toxic gases with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. May form flammable gases with alkali metals. Explosive combination may occur with strong oxidizing agents, metal salts, peroxides, and sulfides. Emits toxic fumes of oxides of sulfur and nitrogen when heated to decomposition [Sax, 9th ed., 1996, p. 3165].????
High oral toxicity.????
When heated to decomposition, Acetone thiosemicarbazone emits very toxic fumes of nitrogen oxides and sulfur oxides. Avoid decomposing heat.??? ??
Acetone thiosemicarbazone is used as an intermediate in the manufacture of pharmaceuticals and pesticides. May be used as an agricultural chemical.?? ??
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.? ???
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides??? ??
It is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator.??? ???????? ?? ?? ? ???
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?? ??
??? ???????? ?? ??
???( 211)?? ??
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??? ???????? ?? ??:
????????? ???????? ??????? ???? 2,4-???? ??? ??? ????????
Calcium pyruvate
gloxazone
Phenylacetone
N-METHYLISATIN-3-THIOSEMICARBAZONE
6-AZA-2-THIOTHYMINE
1-Deuteriopropan-2-one
2,3-INDOLEDIONE 3-THIOSEMICARBAZONE
Acetophenone thiosemicarbazone
N1-(4-CHLOROBENZYL)-2-(2-BROMO-1-PHENYLETHYLIDENE)-1-(2-HYDROXYETHYL)HYDRAZINE-1-CARBOTHIOAMIDE
N1-(2,4-DIMETHYLPHENYL)-2-[4-CHLORO-1-(4-FLUOROPHENYL)BUTYLIDENE]HYDRAZINE-1-CARBOTHIOAMIDE
N1-(2-CHLOROPHENYL)-2-(2-BROMO-1-PHENYLETHYLIDENE)-1-METHYLHYDRAZINE-1-CARBOTHIOAMIDE