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??????(???) ??? ???
?? ??:
5308-25-8
???:
??????(???)
???(??):
??????(???);1-??????
???:
1-Ethylpiperazine
???(??):
N-ETHYLPIPERAZINE;NEPRZ;1-Ethylperazine;N-Ethylpiperazin;AKOS BBS-00003610;1-ethyl-piperazin;ETHYLPIPERAZINE-N;1-ETHYLPIPERAZINE;1-ethvlpiperazine;TIMTEC-BB SBB006719
CBNumber:
CB6384137
???:
C6H14N2
??? ??:
114.19
MOL ??:
5308-25-8.mol
MSDS ??:
SDS

??????(???) ??

???
-60 °C
?? ?
157 °C(lit.)
??
0.899 g/mL at 25 °C(lit.)
???
2.48hPa at 20℃
???
n20/D 1.469(lit.)
???
110 °F
?? ??
2-8°C
???
?? ???
??? ??
??
?? ?? (pKa)
9.27±0.10(Predicted)
Specific Gravity
0.899
??
??~???? ???
???
??
??
Air Sensitive
BRN
102971
InChIKey
WGCYRFWNGRMRJA-UHFFFAOYSA-N
LogP
-0.1 at 20℃
CAS ??????
5308-25-8(CAS DataBase Reference)
NIST
N-ethylpiperazine(5308-25-8)
EPA
Piperazine, 1-ethyl- (5308-25-8)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi,Hazard
?? ???? ?? 36/37/38-10
????? 26-36
????(UN No.) UN 1993 3/PG 3
WGK ?? 1
RTECS ?? TM0815500
F ?????? 10-34
?? ?? 3
???? III
HS ?? 29335995
????(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H226 ??? ?? ? ?? ??? ?? ?? 3 ??
H314 ??? ?? ??? ?? ??? ??? ????? ?? ????? ?? 1A, B, C ?? GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H317 ????? ?? ??? ??? ? ?? ?? ??? ?? ?? 1 ?? GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P210 ?·???·??·????? ????? - ?? ???.
P280 ????/???/???/?????? ?????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P303+P361+P353 ??(?? ????)? ??? ??? ?? ??? ??? ????? ??? ?? ????/?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
2
3 0

??????(???) MSDS


1-Ethylpiperazine

??????(???) C??? ??, ??, ??

??? ??

clear colorless to yellow liquid

??

1-Ethylpiperazine is used in the synthesis of 2-(2-methoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1H-benzo[d]imidazole hydrochloride and 2-(5-((4-ethylpiperazin-1-yl)sulfonyl)-2-methoxyphenyl)-1H-benzo[d]imidazole hydrochloride. It is also employed as an intermediate in veterinary medicine, especially in the production of ciproflmoxacin ethyl. Further, it serves as a precursor to prepare dyes.

Synthesis Reference(s)

The Journal of Organic Chemistry, 22, p. 713, 1957 DOI: 10.1021/jo01357a621

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