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????-2

????-2
????-2 ??? ???
?? ??:
131-55-5
???:
????-2
???(??):
????-2;????????????
???:
2,2',4,4'-Tetrahydroxybenzophenone
???(??):
BENZOPHENONE-2;TETRAHYDROXYBENZOPHENONE;UV Absorber Benzophenone-2;70A-196;uvinuld-50;Uvinul D-50;Uvinol D-50;Seesorb 106;Sumisorb 150;Sinosorb? BP-2
CBNumber:
CB6344256
???:
C13H10O5
??? ??:
246.22
MOL ??:
131-55-5.mol
MSDS ??:
SDS

????-2 ??

???
198-200 °C(lit.)
?? ?
349.21°C (rough estimate)
??
1.216
???
1.4825 (estimate)
?? ??
Sealed in dry,Room Temperature
???
DMSO(?? ???, ??? ??), ???(?? ???)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
6.98±0.35(Predicted)
??
??? ?? ?? ??? ??
???
?? ?? ?????.
BRN
1914746
???
???
InChIKey
WXNRYSGJLQFHBR-UHFFFAOYSA-N
LogP
3.091 (est)
CAS ??????
131-55-5(CAS DataBase Reference)
NIST
EPA
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn,Xi
?? ???? ?? 22-36/37/38
????? 26-36-37/39
WGK ?? 3
RTECS ?? DJ1892000
TSCA Yes
HS ?? 29145090
?? ?? ??? 131-55-5(Hazardous Substances Data)
?? LD50 oral in rat: 1220mg/kg
???? ?? KE-03032
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 ????? ?? ??? ??? ? ?? ?? ??? ?? ?? 1 ?? GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
0
2 0

????-2 MSDS


2,2',4,4'-Tetrahydroxybenzophenone

????-2 C??? ??, ??, ??

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yellow to brown crystalline powder

??

2,2',4,4'-Tetrahydroxybenzophenone is a uV-absorber that helps protect against product degradation because of uV-light exposure. It can also mask odor associated with a formulation’s composition.

?? ??

Obtained (small amount) by melting a fluorescin chloride/sodium hydroxide mixture in the presence of a very few water at 230–240° for 2–3 h.

?? ?? ??

BZP-2 is widely used in perfumes to prevent their degradation due to light. It can cause allergic contact dermatitis.

Safety Profile

Moderately toxic by ingestion. Aneye irritant. Mutation data reported. When heated todecomposition it emits toxic fumes of NOx.

Synthesis

2 mol of resorcinol dimethyl ether is added dropwise to a mixture of 1 mol of phosgene and 1 mol of aluminum chloride, and the mixture is heated to 65-80° C at a temperature of 30-40° C in the presence of a chlorinated hydrocarbon selected from aliphatic and aromatic chlorides, such as ethylene dichloride. It is then cooled to 40° C, 2 to 3 mol of aluminum chloride are added, the mixture is heated to 60-70° C, dilute hydrochloric acid is treated with aqueous sodium hydroxide solution, and 2,2',4,4'-Tetrahydroxybenzophenone is isolated by filtration.

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???( 527)?? ??
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