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AC-DEVD-PNA

AC-DEVD-PNA ??? ???
?? ??:
189950-66-1
???:
AC-DEVD-PNA
???(??):
AC-DEVD-P;AC-DEVD-PNA;(2S,5S,8S,11S);ACETYL-DEVD-PNA;AC-DEVD-PNA?, >98%;-11-(carboxymethyl);-8-(2-carboxyethyl);AC-ASP-GLU-VAL-ASP-PNA;-2-(2-Amino-2-oxoethyl);N-Ac-Asp-Glu-Val-Asp-pNA
CBNumber:
CB6203612
???:
C26H34N6O13
??? ??:
638.58
MOL ??:
189950-66-1.mol
MSDS ??:
SDS

AC-DEVD-PNA ??

?? ?
1191.1±65.0 °C(Predicted)
??
1.448±0.06 g/cm3(Predicted)
?? ??
-20°C
???
DMSO(?? ???), ???(?? ???, ??)
??? ??
??
?? ?? (pKa)
2.97±0.10(Predicted)
??
???
???
?(????? ???), ??? ?????, ???, pH 7 ? ??????:???(1:1)(1 mg/ml)? ?????.
???
???

??

WGK ?? 3

AC-DEVD-PNA C??? ??, ??, ??

??

N-Acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-L-asparagine is an para-nitro aniline chromophore cleaved by caspase.

Biochem/physiol Actions

Colorimetric substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.

AC-DEVD-PNA ?? ?? ? ???

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AC-DEVD-PNA ?? ??

???( 119)?? ??
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