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IQHNJQKWEMCXAD-YYZTVXDQSA-N

IQHNJQKWEMCXAD-YYZTVXDQSA-N ??? ???

?? ??:: 709026-60-8

???:: IQHNJQKWEMCXAD-YYZTVXDQSA-N

???(??):: IQHNJQKWEMCXAD-YYZTVXDQSA-N;C16-Sphingosine-1-phosphate;Sphingosine-1-phosphate (d16:1);4-Hexadecene-1,3-diol, 2-amino-, 1-(dihydrogen phosphate), (2S,3R,4E)-

CBNumber:: CB53577025

???:: C16H34NO5P

??? ??:: 351.42

MOL ??:: 709026-60-8.mol

?? ?? 20

IQHNJQKWEMCXAD-YYZTVXDQSA-N ??

?? ?: 528.2±60.0 °C(Predicted)

??: 1.120±0.06 g/cm3(Predicted)

?? ??: Store at -20°C

???: 0.3 M NaOH: 4 mg/ml; DMF: <50 μg/ml; DMSO: <50 μg/ml; PBS (pH 7.2): <50 μg/ml

??? ??: ??? ??

?? ?? (pKa): 1.76±0.10(Predicted)

?? ? ?? ??
?? ? ???? ?? (GHS)

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P271	?? ?? ??? ? ?? ???? ?????.
P280	????/???/???/?????? ?????.
P302+P352	??? ??? ??? ?? ????.
P304+P340	???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P312	???? ??? ????(??)? ??? ????.
P321	(…) ??? ???.
P332+P313	?? ??? ??? ???? ??· ??? ????.
P337+P313	?? ?? ??? ???? ???? ??· ??? ????.
P403+P233	??? ??? ? ?? ?? ??? ???? ?????.
P405	???? ?????.
P501	...? ??? / ??? ?? ???.

NFPA 704

	0
2		0

IQHNJQKWEMCXAD-YYZTVXDQSA-N C??? ??, ??, ??

??

C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate (S1P; ) that binds to S1P₁/EDG-1, S1P₃/EDG-3, and S1P₂/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO cells. C16 S1P was increased in postmortem primary open angle glaucoma trabecular meshwork samples.

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C16-Sphingosine-1-phosphate is an important regulator of a wide variety of biological processes acting as an endogenous ligand to EDG/S1P receptors.

IQHNJQKWEMCXAD-YYZTVXDQSA-N ?? ?? ? ???

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