ChemicalBook >?? ???? >?????

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?? ??:: 1446502-11-9

???:: ?????

???(??):: ?????

???:: Enasidenib

???(??):: NameC;AG-211;AG-221;CS-1590;CC90007;CC 90007;CC-90007;Enasidenib;AG221;AG 221;Enasidenib(AG-221)

CBNumber:: CB53044318

???:: C19H17F6N7O

??? ??:: 473.38

MOL ??:: 1446502-11-9.mol

?? ?? 161

????? ??

???: 168-170°C

?? ?: 581.0±60.0 °C(Predicted)

??: 1.477±0.06 g/cm3(Predicted)

?? ??: -20°C

???: DMSO? ???(?? 25mg/ml)

??? ??: ??

??? ??: ??? ??

?? ?? (pKa): 14.70±0.29(Predicted)

??: ???

???: ??? ?? ?????? 1? ?? ??????. DMSO ??? -20°C?? ?? 3?? ?? ??? ? ????.

?? ? ?? ??
?? ? ???? ?? (GHS)

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H302	??? ???	?? ?? ?? - ??	?? 4	??	P264, P270, P301+P312, P330, P501
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P280	????/???/???/?????? ?????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

NFPA 704

	0
2		0

????? C??? ??, ??, ??

??

Enasidenib is a first-in-class oral selective inhibitor of mutant IDH2 enzymes (isocitrate dehydrogenase 2), for the treatment of adults with relapsed or refractory IDH2-mutated acute myeloid leukemia.

????? ?? ?? ? ???

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???( 161)?? ??

???	??	???	??	?? ?	??
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
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InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
Nanjing Doge Biomedical Technology Co., Ltd	+86-25-58227606 +86-15305155328	sales@dogechemical.com	China	4128	58

????? ?? ??:

SH-4-54 Osimertinib mesylate Tazemetostat (EPZ-6438) Niraparib Mertansine (S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate Ivosidenib ABBV-075 Ponatinib Selonsertib 4-chloro-6-(6-(trifluoromethyl)pyridin-2-yl)-N-(2-(trifluoromethyl)pyridin-4-yl)-1,3,5-triazin-2-amine Abemaciclib AG-120 AZD6738 BLU 9931 2-(2-Chlorophenyl)-4-(3-(diMethylaMino)phenyl)-5-Methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione RVX-208 Epacadostat (INCB024360)

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