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2,4-????-7,7-???-5,7-???????[3,4-d]????

2,4-????-7,7-???-5,7-???????[3,4-d]????
2,4-????-7,7-???-5,7-???????[3,4-d]???? ??? ???
?? ??:
1260088-72-9
???:
2,4-????-7,7-???-5,7-???????[3,4-d]????
???(??):
2,4-????-7,7-???-5,7-???????[3,4-d]????
???:
2,4-Dichloro-7,7-diMethyl-5,7-dihydrofuro[3,4-d]pyriMidine
???(??):
2,4-dichloro-7,7-dimethyl-5H-furo[3,4-d]pyrimidine;2,4-dichloro-7,7-dimethyl-5H,7H-furo[3,4-d]pyrimidine;2,4-Dichloro-7,7-diMethyl-5,7-dihydrofuro[3,4-d]pyriMidine;2,4-dichloro-5,7-dihydro-7,7-dimethylFuro[3,4-d]pyrimidine;Furo[3,4-d]pyrimidine, 2,4-dichloro-5,7-dihydro-7,7-dimethyl-
CBNumber:
CB52658752
???:
C8H8Cl2N2O
??? ??:
219.07
MOL ??:
1260088-72-9.mol

2,4-????-7,7-???-5,7-???????[3,4-d]???? ??

?? ?
317.6±42.0 °C(Predicted)
??
1.383±0.06 g/cm3(Predicted)
?? ??
under inert gas (nitrogen or Argon) at 2-8°C
?? ?? (pKa)
-3.37±0.40(Predicted)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
HS ?? 2933599590
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 ???? ??? ?? ?? ?? ?? ?? 4 ?? GHS hazard pictograms P261, P271, P304+P340, P312
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P280 ????/???/???/?????? ?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

2,4-????-7,7-???-5,7-???????[3,4-d]???? C??? ??, ??, ??

??

2,4-Dichloro-5,7-dihydro-7,7-dimethylfuro[3,4-d]pyrimidine is used for preparation and study of pharmacokinetics, and antitumor activity of dihydrofuro[3,4-d]pyrimidines as inhibitors of mammalian target of rapamycin kinase.

2,4-????-7,7-???-5,7-???????[3,4-d]???? ?? ?? ? ???

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?? ??


2,4-????-7,7-???-5,7-???????[3,4-d]???? ?? ??

???( 45)?? ??
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