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Alpidem

Alpidem ??? ???
?? ??:
82626-01-5
???:
Alpidem
???(??):
ALPIDEM;IMidazo;inanxyl;Ananxyl;Alpidemum;SL-80.0342;SL 80.0342-00;Unii-I93sc245qz;Alpidemum [latin];ALPIDEM USP/EP/BP
CBNumber:
CB5241330
???:
C21H23Cl2N3O
??? ??:
404.33
MOL ??:
82626-01-5.mol

Alpidem ??

???
136-138°C
??
1.24±0.1 g/cm3(Predicted)
?? ??
Refrigerator
???
DMSO: ≥10mg/mL
?? ?? (pKa)
4.74±0.50(Predicted)
??? ??
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  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictograms
?? ?: Warning
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?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
??????:
P280 ????/???/???/?????? ?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
0
2 0

Alpidem C??? ??, ??, ??

??

Alpidem is an imidazopyridine antianxiety agent with anticonvulsant properties. It is claimed to be the first non-benzodiazepine anxiolytic to show selectivity for the omega-1 modulatory site of the GABA, receptors. Alpidem is reported to be superior to buspirone and similar to the benzodiazepines, but is significantly better tolerated with lower abuse potential.

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White to Off-White Solid

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A peripheral benzodiazepine GABAA receptor ligand, a new anxiolytic

Alpidem ?? ?? ? ???

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Alpidem ?? ??

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Alpidem ?? ??:

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