ChemicalBook >?? ???? >ANTI-STROMELYSIN-2
ANTI-STROMELYSIN-2
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ANTI-STROMELYSIN-2 ??
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Anti-ST2 has been used in immunohistochemistry, western blottingand immunofluorescence staining.?? ??
ST2 (suppression of tumorigenicity) belongs to the IL-1 family of cytokines. It is also known as IL-33 (interleukin 33) and IL1RL1 (interleukin 1 receptor like 1). It is expressed in macrophages and various inflammatory cells like T helper 2 (Th2), mast cells, basophils and eosinophils. It is mapped to chromosome 2q12.Biochem/physiol Actions
ST2 (suppression of tumorigenicity) participates in pathophysiology of several diseases like asthma, arthritis, obesity and atherosclerosis. It works as a mitogen in eosinophils, fibrocytes, endothelial cells. It helps in the migration of Th2 lymphocytes, fibrocytes and endothelial cells, and disturbs the incursion and metastasis of breast tumor.ANTI-STROMELYSIN-2 ?? ?? ? ???
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