ChemicalBook >?? ???? >??4-[2-(5-???-2-????????)??]????????????

??4-[2-(5-???-2-????????)??]????????????

??4-[2-(5-???-2-????????)??]???????????? ??? ???

?? ??:: 14511-59-2

???:: ??4-[2-(5-???-2-????????)??]????????????

???(??):: ??4-[2-(5-???-2-????????)??]????????????

???:: Ethyl 4-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzene Sulfonamide Carbamate

???(??):: Glibenclamide Impurity 10;Ethyl (4-(2-(5-chloro-2-methoxybenzamido)ethyl)phenyl)sulfonylcarbamate;[[4-[2-[(5-chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonyl]Carbamic acid;[p-[2-(5-chloro-o-anisamido)ethyl]phenyl]sulfonyl]Carbamic acid, [ethyl ester;ethyl N-(4-{2-[(5-chloro-2-methoxyphenyl)formamido]ethyl}benzenesulfonyl)carbamate;Carbamic acid,[[4-[2-[(5-chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonyl]-,ethyl ester;[[4-[2-[(5-chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonyl]Carbamic acid, , ethyl ester;Carbamic acid, N-[[4-[2-[(5-chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonyl]-, ethyl ester;Glibenclamide ImpurityⅡ:Ethyl 4-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzene Sulfonamide Carbamate;Glibenclamide ImpurityⅡ:Ethyl 4-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzene Sulfonamide Carbamate

CBNumber:: CB51176325

???:: C19H21ClN2O6S

??? ??:: 440.9

MOL ??:: 14511-59-2.mol

?? ?? 42

??4-[2-(5-???-2-????????)??]???????????? ??

???: 154-155°C

??: 1.335±0.06 g/cm3(Predicted)

???: DMSO(?? ???, ??), ???(?? ???)

?? ?? (pKa): 4.73±0.10(Predicted)

??? ??: ??

??? ??: ??? ??

??: ???? ?????

?? ? ?? ??
?? ? ???? ?? (GHS)

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H302	??? ???	?? ?? ?? - ??	?? 4	??	P264, P270, P301+P312, P330, P501
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P270	? ??? ??? ??? ???, ???? ???? ???.
P271	?? ?? ??? ? ?? ???? ?????.
P280	????/???/???/?????? ?????.
P301+P312	??? ???? ??? ????(??)? ??? ????.
P302+P352	??? ??? ??? ?? ????.
P304+P340	???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P330	?? ?????.
P332+P313	?? ??? ??? ???? ??· ??? ????.
P337+P313	?? ?? ??? ???? ???? ??· ??? ????.
P362	??? ??? ?? ?? ?? ?????
P403+P233	??? ??? ? ?? ?? ??? ???? ?????.
P405	???? ?????.
P501	...? ??? / ??? ?? ???.

??4-[2-(5-???-2-????????)??]???????????? C??? ??, ??, ??

??? ??

Off-White Solid

??

An impurity arising in the synthesis of Glyburide (G598350).

??4-[2-(5-???-2-????????)??]???????????? ?? ?? ? ???

???

?? ??

??4-[2-(5-???-2-????????)??]???????????? ?? ??

???( 42)?? ??

???	??	???	??	?? ?	??
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??4-[2-(5-???-2-????????)??]???????????? ?? ??:

Ginkgolide J Ginsenoside Rc Ginsenoside Rg1 Ginsenoside Rb1 Ginkgolide C Ginkgolide K Ginsenoside Re Ginkgolide B Ginkgolide A S-Etodolac Ethyl2,5-dihydro-5-oxo-1-phenyl-1H-1,2,4-triazole-3-carboxylate ETHYL ([3-(METHYLTHIO)-1,2,4-THIADIAZOL-5-YLTHIO]METHYL) CYANOCARBONIMIDODITHIOATE ETHYL 4-(4-TERT-BUTYLPHENYL)-5-CYANAMIDE-4,5-DIHYDRO-1,3,4-THIADIAZOLE-2-CARBOXYLATE Ethyl1-(2,4-dichlorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxylate ETHYL 5-CYANAMIDE-4-(3,5-DICHLOROPHENYL)-4,5-DIHYDRO-1,3,4-THIADIAZOLE-2-CARBOXYLATE ethyl 3-bromomethylphenoxyacetate ETHYL 4-[4-CHLORO-2-(TRIFLUOROMETHYL)PHENYL]-5-CYA NAMIDE-4,5-DIHYDRO-1,3,4-THIADIAZOLE-2-CARBOXYLATE (ETHOXYCARBONYLMETHYL)DIPHENYLPHOSPHINE

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