ChemicalBook >?? ???? >Pivampicillin Hydrochloride
Pivampicillin Hydrochloride
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Pivampicillin Hydrochloride ??
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- 155-156° (decomp)
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- D20 +196° (c = 1 in water)
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- Hygroscopic, -20°C Freezer, Under inert atmosphere
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- DMSO (?? ???), ? (?? ???,?????)
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- pKa ~7.0(at 25℃)
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| ?? | LD50 in mice, rats (g/kg): 3.34, 5.00 orally; 3.60, 4.50 s.c. (von Daehne) | ||
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| ???? ?? | KE-05-1050 |
Pivampicillin Hydrochloride C??? ??, ??, ??
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Semi-synthetic antibiotic related to Penicillin (P223500). Antibacterial.?? ?? ??
Pivampicillin is a prodrug of ampicillin. It caused sensitization in 56 workers at a penicillin factory. Pivampicillin and pivmecillinam were responsible for contact dermatitis in pharmaceutical production workers. Ampicillin, mecillinam or amdinocillin, penicillin V and penicillin G were also implicated in cross-reactions.Safety Profile
Moderately toxic by ingestion andsubcutaneous routes. When heated todecomposition it emits very toxic fumes of NOx, SOx, andHCl.Pivampicillin Hydrochloride ?? ?? ? ???
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Pivampicillin Hydrochloride ?? ??
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| ??? | ?? | ??? | ?? | ?? ? | ?? |
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| TargetMol Chemicals Inc. | |
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