Metolazone
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Metolazone ??
- ???
- 252-254°C
- ?? ?
- 613.6±65.0 °C(Predicted)
- ??
- 1.2895 (rough estimate)
- ???
- 1.6100 (estimate)
- ?? ??
- 2-8°C
- ???
- ? ??? DMSO: >5mg/mL
- ?? ?? (pKa)
- pKa 9.7 (Uncertain)
- ??? ??
- ??
- ??? ??
- ??? ??
- ??
- ???
- ???
- 60.3mg/L(25℃)
- ???
- ??? ??? 2? ?? ??????. DMSO ??? -20°C?? ?? 2?? ?? ?? ??? ? ????.
- InChIKey
- AQCHWTWZEMGIFD-UHFFFAOYSA-N
- CAS ??????
- 17560-51-9(CAS DataBase Reference)
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| WGK ?? | 2 | ||
|---|---|---|---|
| RTECS ?? | VA1700000 | ||
| HS ?? | 2935904000 | ||
| ?? ?? ??? | 17560-51-9(Hazardous Substances Data) | ||
| ?? | LD50 in mice (mg/kg): >5000 orally; >1500 i.p. (Shetty, 1967) |
Metolazone C??? ??, ??, ??
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Metolazone (Item No. 26304) is an analytical reference standard categorized as a diuretic. It has been detected as an adverse analytical finding (AAF) during anti-doping testing. This product is intended for use in analytical forensic applications. This product is also available as a general research tool .??? ??
Crystalline Solid??
Metolazone acts on the distal tubules, thus increasing excretion of water and sodium, potassium, and chloride ions. It is used for treating edema caused by cardiac insufficiency and adrenal irregularities, including nephrotic syndrome.??
ChEBI: A quinazoline that consists of 1,2,3,4-tetrahydroquinazolin-4-one bearing additional methyl, 2-tolyl, sulfamyl and chloro substituents at positions 2, 3, 6 and 7 respectively. A quinazoline diuretic, with properties similar to thiazide diuretics.Metolazone ?? ?? ? ???
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Metolazone ?? ??
???( 169)?? ??
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