ChemicalBook >?? ???? >BPV(??)
BPV(??)
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BPV(??) ??
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- -20°C
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- H2O: ???20mg/mL, ??
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- water: 4mg/mL
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bpV(HOpic) has been used in pharmacological perturbation of cell migration related signaling pathway.Biochem/physiol Actions
bpV(OHpic) is a bisperoxovanadium inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumour suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(HOpic) are 14 nM for PTEN compared to 4.9 μM for PTPβ and 25.3 μM for PTP-1β. bpV(HOpic) has been shown to enhance PI3K/Akt signaling that could prevent myocardium from ischemia-reperfusion injury.BPV(??) ?? ?? ? ???
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