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DL-????-[S,R]-????

DL-????-[S,R]-????
DL-????-[S,R]-???? ??? ???
?? ??:
5072-26-4
???:
DL-????-[S,R]-????
???(??):
DL-????-[S,R]-????
???:
DL-BUTHIONINE-[S,R]-SULFOXIMINE
???(??):
NSC 381100;butioninesulfoximine;buthioninesulfoximine;buthioninesulfoxamine;buthioninesulphoximine;DL-BUTHIONINE-SULFOXIMINE;DL-BUTHIONINE (S,R)-SULPHOXIME;DL-BUTHIONINE-[S,R]-SULFOXIMINE;DL-BUTHIONINE (R,S)-SULFOXIMINE;DL-Buthionine-sulfoximine
CBNumber:
CB4184630
???:
C8H18N2O3S
??? ??:
222.31
MOL ??:
5072-26-4.mol
MSDS ??:
SDS

DL-????-[S,R]-???? ??

???
215 °C (dec.)(lit.)
?? ?
382.3±52.0 °C(Predicted)
??
1.29±0.1 g/cm3(Predicted)
?? ??
2-8°C
???
H2O: 50 mg/mL, ??, ??
??? ??
??? ??
??
???
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synthetic (organic)
???
water: 50mg/mL, clear to very slightly hazy, colorless to yellow
Merck
13,1520
BRN
2367136
CAS ??????
5072-26-4(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 26-36
WGK ?? 3
RTECS ?? EK7713435
F ?????? 10
HS ?? 29309090
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
0
2 0

DL-????-[S,R]-???? C??? ??, ??, ??

??? ??

White Crystalline Solid

??

A potent and specific inhibitor of alpha-glutamyl cysteine synthetase

??

ChEBI: A sulfoximide that is the sulfoximine derivative of an analogue of DL-methionine in which the S-methyl group is replaced by S-butyl.

?? ??

DL-buthionine-SR-sulfoximine (BSO) is an amino acid analogue, which acts as an inhibitor of γ-glutamylcysteine synthetase. BSO increases the sensitivity of Trypanosoma cruzi to antiparasitic drugs, such as nifurtimox or benznidazole.

DL-????-[S,R]-???? ?? ?? ? ???

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DL-????-[S,R]-???? ?? ??

???( 90)?? ??
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