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N-?????-N-?????

N-?????-N-?????
N-?????-N-????? ??? ???
?? ??:
94-34-8
???:
N-?????-N-?????
???(??):
N-?????-N-?????
???:
N-(2-Cyanoethyl)-N-methylaniline
???(??):
N-Methyl-N-Cyanoethyl Aniline;N-CYANOETHYL-N-METHYL ANILINE;3-(N-METHYLANILINO)PROPIONITRILE;N-(2-CYANOETHYL)-N-METHYLANILINE;N-(B-CYANOETHYL)-N-METHYLANILINE;N-METHYL-N-(B-CYANOETHYL)ANILINE;N-METHYL-N-(2-CYANOETHYL)ANILINE;3-(N-methylanilino)propanenitrile;3-(N-methylanilino)propiononitrile;3-(METHYLPHENYLAMINO)PROPIONITRILE
CBNumber:
CB3451771
???:
C10H12N2
??? ??:
160.22
MOL ??:
94-34-8.mol
MSDS ??:
SDS

N-?????-N-????? ??

?? ?
313 °C(lit.)
??
1.035 g/mL at 25 °C(lit.)
???
n20/D 1.56(lit.)
???
125-127°C/4mm
?? ??
Inert atmosphere,Room Temperature
??? ??
??? ??
?? ?? (pKa)
4.54±0.50(Predicted)
??
White to Yellow to Green
Specific Gravity
1.05
BRN
2803416
CAS ??????
94-34-8(CAS DataBase Reference)
EPA
Propanenitrile, 3-(methylphenylamino)- (94-34-8)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 20/21/22-36/37/38-21/22
????? 26-36-36/37
WGK ?? 3
TSCA Yes
???? III
HS ?? 29214300
???? ?? KE-24804
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 ??? ???? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P501 ...? ??? / ??? ?? ???.
NFPA 704
0
2 0

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Synthesis

An activated carbon-supported platinum catalyst (Pt / C, 0.06 mg platinum, 0.0003 mmol, 0.1 mol percent) was added to a 10 mL Schlenk tube; after the evacuation of argon, add 1 mL of solvent (toluene). Under argon protection, to the above system, Were successively added phenylsilane (78.9 mg, 0.75 mmol), 3-Anilinopropionitrile (43.9 mg, 0.3 mmol) and formic acid (27.6 mg, 0.6 mmol). The whole anti-reaction was carried out at 80 ° C with stirring for 15 hours. After completion of the reaction, 3 mL of ethyl acetate was added to the system. The reaction was quenched with aqueous sodium hydroxide (3 mol / L, 3 mL). Ethyl acetate (3 x 10 mL), the organic phase was separated, Dried over anhydrous Na2SO4, and filtered; the solvent was removed by rotary evaporation. The residue was purified by column chromatography on ethyl acetate/petroleum ether = 1: 50 mixed solvent. Separation and purification gave N-(2-Cyanoethyl)-N-methyl aniline 226.4 mg, yield of 55 per cent.

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