ChemicalBook >?? ???? >??????

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?? ??:: 175013-84-0

???:: ??????

???(??):: ??????

???:: TONABERSAT

???(??):: SB 22045;SB 220453;TONABERSAT;SB 220453;SB220453;Tonabersat [ban, inn];Tonabersat (SB-220453);Tonabersat >=98% (HPLC);SB-220453;SB 220453;SB220453;N-((3S,4S)-6-Acetyl-3-hydroxy-2,2-diMethylchroMan-4-yl)-3-chloro-4-fluorobenzaMide;2H-Benzo(B)pyran-3-ol, 6-acetyl-4-(3-chloro-4-fluorobenzoylamino)-3,4-dihydro-2,2-dimethyl-

CBNumber:: CB3406968

???:: C20H19ClFNO4

??? ??:: 391.82

MOL ??:: 175013-84-0.mol

MSDS ??:: SDS

?? ?? 92

?????? ??

?? ?: 554.5±50.0 °C(Predicted)

??: 1.38

?? ??: 2-8°C

???: DMSO? ???

?? ?? (pKa): 11.86±0.60(Predicted)

??? ??: ??

??: ???? ????

optical activity: [α]/D -100 to -110°, c = 1 in methanol

?? ? ?? ??
?? ? ???? ?? (GHS)

????(UN No.)	UN 3077 9 / PGIII

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H400	????? ?? ???	?? ????? ?? - ??	?? 1	??	P273, P391, P501

??????:

P273	???? ???? ???.
P280	????/???/???/?????? ?????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P337+P313	?? ?? ??? ???? ???? ??· ??? ????.
P391	???? ????.

NFPA 704

	0
2		0

?????? C??? ??, ??, ??

Biochem/physiol Actions

Tonabersat (SB-220453) exhibits anticonvulsant property. It is a member of the family of novel benzoylamino-benzopyran compounds. Tonabersat is used as a therapeutic for trigeminal nerve-induced neurovascular reflexes. In addition, it acts as a putative migraine prophylactic agent containing an unique stereospecific binding site in the brain.

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???( 92)?? ??

???	??	???	??	?? ?	??
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32159	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9638	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38630	58
Aladdin Scientific		tp@aladdinsci.com	United States	52924	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chembest Research Laboratories Limited	+86-21-20908456	sales@BioChemBest.com	China	6005	61
Beijing HuaMeiHuLiBiological Chemical	010-56205725	waley188@sohu.com	China	12335	58

?????? ?? ??:

3-CHLORO-4-FLUOROBENZAMIDE 2,2-DIMETHYLCHROMANE-6-CARBALDEHYDE (R)-1-(2-Methoxyphenyl)ethylamine 3-M-TOLYL-DL-BETA-ALANINOL 3-Chloro-4-fluorobenzylamine 3-Chloro-4-fluorobenzaldehyde (R)-m-Methyl-a-phenethylamin 2H-1-Benzopyran-4-amine,3,4-dihydro-,(4R)-(9CI) CHEMBRDG-BB 4004528 CHEMBRDG-BB 5942726 (R)-(+)-N-BENZOYL-ALPHA-METHYLBENZYLAMINE N-(4-fluorobenzyl)-N-(1-phenylethyl)amine TONABERSAT 6-METHYL-CHROMAN-4-YLAMINE HYDROCHLORIDE (S)-(-)-1-BENZYLAMINO-3-PHENOXY-2-PROPANOL CHEMBRDG-BB 4004364 CHROMAN-4-YL-AMMONIUM CHLORIDE (R)-(+)-N-BENZYL-1-PHENYLETHYLAMINE HYDROCHLORIDE

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