ChemicalBook >?? ???? >4-???-3-????????-1-???,2-??-4-[(????-1-?)???]???

4-???-3-????????-1-???,2-??-4-[(????-1-?)???]???

4-???-3-????????-1-???,2-??-4-[(????-1-?)???]??? ??? ???

?? ??:: 457961-34-1

???:: 4-???-3-????????-1-???,2-??-4-[(????-1-?)???]???

???(??):: 4-???-3-????????-1-???,2-??-4-[(????-1-?)???]???

???:: 4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole

???(??):: Cy1001;AA92593;AA92593 >=98% (HPLC);1-(4-Methoxy-3-methyl-benzenesulfonyl)-piperidine;1-[(4-Methoxy-3-methylphenyl)sulphonyl]piperidine;Piperidine, 1-[(4-methoxy-3-methylphenyl)sulfonyl]-;Per1,AA-92593,Melanopsin,α-MSH,AA92593,inhibit,Inhibitor,OPN4,AA 92593,Melanoma,CHO;4-Methoxy-3-methylphenyl piperidin-1-yl sulphone, 2-Methyl-4-[(piperidin-1-yl)sulphonyl]anisole

CBNumber:: CB32696509

???:: C13H19NO3S

??? ??:: 269.36

MOL ??:: 457961-34-1.mol

MSDS ??:: SDS

?? ?? 45

4-???-3-????????-1-???,2-??-4-[(????-1-?)???]??? ??

?? ??: -20°C

???: DMSO: ???10mg/mL, ??

??? ??: ??

??: ???? ????

?? ? ?? ??
?? ? ???? ?? (GHS)

??? ??	Xi
?? ???? ??	36-37-38
?????	26
WGK ??	3
HS ??	2933998090

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P271	?? ?? ??? ? ?? ???? ?????.
P280	????/???/???/?????? ?????.
P302+P352	??? ??? ??? ?? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

NFPA 704

	0
2		0

4-???-3-????????-1-???,2-??-4-[(????-1-?)???]??? C??? ??, ??, ??

??

AA92593 has been used as a selective melanopsin inhibitor.

Biochem/physiol Actions

AA92593 is an opsinamide, a potent antagonist of melanopsin-mediated phototransduction with an IC50 of 665 nM in a Ca2+ flux assay in CHO cells expressing melanopsin (Opn4) and selectivity > 10 μM at 74 common biological targets. AA41612 is believed to act by competing for binding to melanopsin. AA41612 inhibited mouse pupillary light reflex and light aversion in vivo. AA92593 and similar compounds might be useful in alleviating the photophobia associated with migraine.

4-???-3-????????-1-???,2-??-4-[(????-1-?)???]??? ?? ?? ? ???

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4-???-3-????????-1-???,2-??-4-[(????-1-?)???]??? ?? ??

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???	??	???	??	?? ?	??
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4-???-3-????????-1-???,2-??-4-[(????-1-?)???]??? ?? ??:

METHYLERGONOVINE 1-Methylpyrazole Methyl stenbolone

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