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fumagillol

fumagillol ??? ???
?? ??:
108102-51-8
???:
fumagillol
???(??):
Fumagillol,Bacterial,inhibit,Inhibitor;(3R,4S,5S,6R)-5-Methoxy-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-1-oxaspiro[2.5]octan-6-ol;1-Oxaspiro[2.5]octan-6-ol, 5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-, (3R,4S,5S,6R)-
CBNumber:
CB31381347
???:
C16H26O4
??? ??:
282.38
MOL ??:
108102-51-8.mol

fumagillol ??

???
54-56 °C(Solv: ligroine (8032-32-4))
?? ?
140 °C(Press: 0.02 Torr)
??
1.13±0.1 g/cm3(Predicted)
?? ??
Store at -20°C
???
DMSO : 100 mg/mL (354.13 mM; Need ultrasonic)
??? ??
??
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?? ?? (pKa)
14.21±0.60(Predicted)
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fumagillol C??? ??, ??, ??

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Fumagillol is an analog of Fumagillin (F862650), a compound isolated from the fungus Aspergillus fumigatus. Fumagillin is an antimicrobial agent used in the treatment of microsporidiosis. Fumagillin shows promise as both an an anti-infective and antiangiogenic agent.

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