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Sirt2-PROTAC-1

Sirt2-PROTAC-1 ??? ???
?? ??:
2098487-75-1
???:
Sirt2-PROTAC-1
???(??):
Sirt2-PROTAC-1;PROTAC Sirt2 Degrader-1;N-{4-[4-({3-[(2-{2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetamido}-1,3-thiazol-5-yl)methyl]phenoxy}methyl)-1H-1,2,3-triazol-1-yl]butyl}-2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetamide
CBNumber:
CB24668512
???:
C40H40N10O8S2
??? ??:
852.94
MOL ??:
2098487-75-1.mol

Sirt2-PROTAC-1 ??

??
1.52±0.1 g/cm3(Predicted)
?? ??
Store at -20°C
???
DMSO : ≥ 100 mg/mL (117.24 mM);Water : < 0.1 mg/mL (insoluble)
??? ??
Solid
?? ?? (pKa)
7.94±0.50(Predicted)
??
White to off-white

??

Sirt2-PROTAC-1 C??? ??, ??, ??

Sirt2-PROTAC-1 ?? ?? ? ???

???

?? ??


Sirt2-PROTAC-1 ?? ??

???( 19)?? ??
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