Sertaconazole nitrate
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Sertaconazole nitrate ??
- ???
- 158-160°
- ?? ??
- -20°C
- ???
- DMSO: ???20mg/mL, ??
- ??? ??
- ??
- ?? ?? (pKa)
- pKb: 7.26(at 25℃)
- ??
- ???? ????
- InChIKey
- HAAITRDZHUANGT-UHFFFAOYSA-N
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| WGK ?? | 3 |
|---|
Sertaconazole nitrate C??? ??, ??, ??
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Sertaconazole nitrate is a new broad spectrum imidazole antifungal agent introduced in a topical formulation for the treatment of cutaneous infections. Its mechanism of action is the inhibition of ergosterol synthesis and interference with the permeability of fungus cell membranes. An oral formulation is currently under investigation for the treatment of bucco-pharyngeal fungal infections.??? ??
Off-White Solid??
An imidazole antifungal agent, inhibits the synthesis of ergosterol, an essential cell wall component of fungi.Sertaconazole nitrate ?? ?? ? ???
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Sertaconazole nitrate ?? ??
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