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1163-36-6
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???(??):
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Clemizole hydrochloride
???(??):
p48;CS-1763;allercur;CLEMIZOLE HCL;allercurehydrochloride;LABOTEST-BB LT00453174;CLEMIZOLE HYDROCHLORIDE;Clemizole hydrochloride, >=98%;1-(P-CHLOROBENZYL)-2-(1-PYRROLIDINYLMETHYL)-BENZIMIDAZOL;1-(p-chlorobenzil)-2-pirrolidil-metil-benzimidazolocloridato
CBNumber:
CB0484200
???:
C19H21Cl2N3
??? ??:
362.3
MOL ??:
1163-36-6.mol
MSDS ??:
SDS

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239-241°
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Inert atmosphere,2-8°C
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H2O: ???2mg/mL, ??(???)
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??
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16.84mg/L at 25℃
Merck
14,2346
InChIKey
DNFMJYXRIMLMBZ-UHFFFAOYSA-N
LogP
1.99
CAS ??????
1163-36-6(CAS DataBase Reference)
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  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 22
????? 36
WGK ?? 3
RTECS ?? DD6730000
HS ?? 2933.99.8290
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
??????:
NFPA 704
0
1 0

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Clemizole Hydrochloride inhibits Hepatitis C RNA replication in cell culture through the suppression of the binding between the nonstructural protein 4B and the viral RNA genome with little toxicity for the host cell. Clemizole Hydrochloride is also a potent inhibitor of transient receptor potential channel TRPC5.

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