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2-Fluoropyridine-5-carboxaldehyde

2-Fluoropyridine-5-carboxaldehyde ??? ???
?? ??:
677728-92-6
???:
2-Fluoropyridine-5-carboxaldehyde
???(??):
6-Fluoronicotinaldehyde;6-fluoropyridine-3-carbaldehyde;2-FLUORO-5-FORMYLPYRIDINE;2-FLUOROPYRIDINE-5-CARBALDEHYDE;6-Fluoropyridine-3-Carboxaldehyde;2-Fluoro-5-pyridinecarboxaldehyde;2-Fluoropyridine-5-carboxaldehyde;3-Pyridinecarboxaldehyde, 6-fluoro-;3-Pyridinecarboxaldehyde,6-fluoro-(9CI);2-Fluoropyridine-5-carboxaldehyde ISO 9001：2015 REACH
CBNumber:
CB0228297
???:
C6H4FNO
??? ??:
125.1
MOL ??:
677728-92-6.mol

2-Fluoropyridine-5-carboxaldehyde ??

?? ?
229.0±20.0 °C(Predicted)
??
1.269±0.06 g/cm3(Predicted)
?? ??
under inert gas (nitrogen or Argon) at 2-8°C
?? ?? (pKa)
-2.23±0.10(Predicted)
??? ??
??? ??
??
???
InChI
InChI=1S/C6H4FNO/c7-6-2-1-5(4-9)3-8-6/h1-4H
InChIKey
PZPNGWWKCSJKOS-UHFFFAOYSA-N
SMILES
C1=NC(F)=CC=C1C=O
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
????(UN No.) 1993
?? ?? ?? Irritant
?? ?? 3
???? Ⅲ
HS ?? 2933399990
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 ??? ???? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 ???? ??? ?? ?? ?? ?? ?? 4 ?? GHS hazard pictograms P261, P271, P304+P340, P312
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P280 ????/???/???/?????? ?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

2-Fluoropyridine-5-carboxaldehyde C??? ??, ??, ??

??

6-Fluoro-3-pyridinecarboxaldehyde is used in the synthetic preparation of biheteroaryl arylamines as selective inhibitors of phosphoinositol 3-kinases (PI3K), which are selective for PI3K over mTOR and have potential use as antitumor agents.

2-Fluoropyridine-5-carboxaldehyde ?? ?? ? ???

???

????? N,N-????????? ????? ??? ?? ????????? ?????? ???? 2-Amino-5-bromopyridine ???????? ?????? ????? ?? ?? ?? ????

?? ??

3-Pyridinecarboxaldehyde, 6-(2-methyl-1H-imidazol-1-yl)-

2-Fluoropyridine-5-carboxaldehyde ?? ??

???( 198)?? ??
??? ?? ??? ?? ?? ? ??
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2-Fluoropyridine-5-carboxaldehyde ?? ??:

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