ChemicalBook >?? ???? >API>??? ??>? ????>L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid ??? ???

?? ??:: 74163-81-8

???:: L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

???(??):: Tic-OH;(S)-TIC;L-TIC HCL;L-1,2,3,4-Tetrahydro;Icatibant Impurity 14;Quinapril Bicyclic Acid;Quinapril EP Impurity A;(S)-1,2,3,4-Tetrahydro-3-isoquinoL;(3S)-1,2,3,4-Tetrahydroisoquinoline;Quinapril Hydrochloride EP Impurity A

CBNumber:: CB0197924

???:: C10H11NO2

??? ??:: 177.2

MOL ??:: 74163-81-8.mol

MSDS ??:: SDS

?? ?? 325

L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid ??

???: >300 °C(lit.)

??: -157.4 º (24 ºC)

?? ?: 309.12°C (rough estimate)

??: 1.1607 (rough estimate)

???: -166 ° (C=1, 1mol/L NaOH)

?? ??: Keep in dark place,Inert atmosphere,2-8°C

???: soluble in Hot Water, Basic Water

??? ??: powder to crystal

?? ?? (pKa): 2.21±0.20(Predicted)

??: ???? ?? ??

optical activity: [α]20/D 168°, c = 1.8 in 1.4 M NaOH

BRN: 4842199

InChIKey: BWKMGYQJPOAASG-VIFPVBQESA-N

CAS ??????: 74163-81-8(CAS DataBase Reference)

?? ? ?? ??
?? ? ???? ?? (GHS)

??? ??	Xi
?? ???? ??	36/37/38
?????	26-36-37/39
WGK ??	3
HS ??	29334900

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P271	?? ?? ??? ? ?? ???? ?????.
P280	????/???/???/?????? ?????.
P302+P352	??? ??? ??? ?? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

NFPA 704

	1
2		0

L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid C??? ??, ??, ??

??? ??

white to light yellow crystal powde

L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid ?? ?? ? ???

???

?? ??

(S)-N-tert-??-1,2,3,4-???????????-3-??????? 2-BENZOYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID (3S)-7-nitro-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid 1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLICACID?????? 1,2,3,4-??????-?????-3-??????????? ??(3S)-1,2,3,4-????????????-3-?????????

L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid ?? ??

???( 325)?? ??

???	??	???	??	?? ?	??
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L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid ?? ??:

??????-1-????? ??? ?? ??? ???????? ??????? ???????? ????? ????????? 3-???????? 1,2,3,4-Tetrahydroquinoline 1,2,3,4-TETRAHYDROISOQUINOLINE cis-1,2,3,6-Tetrahydrophthalic anhydride 5,6,7,8-TETRAHYDROISOQUINOLINE 2-Tetrahydrofuroic acid H-TLE-OTBU HCL H-Tic-OMe·HCl L-tert-Leucine methyl ester hydrochloride H-Tic-OtBu·HCl (S)-6,7-Dimethoxy-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride Quinapril hydrochloride Moexipril

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