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6-Methoxyguanine

6-Methoxyguanine ??? ???
?? ??:
20535-83-5
???:
6-Methoxyguanine
???(??):
NSC 37364;O-METHYLGUANINE;O6-METHYLGUANINE;6-Methoxyguanine;6-O-Methylguanine;o(sup6)-methylguanine;6-O-Methylguanine 97%;Aminomethoxypurine,97%;Nelarabine Impurity 11;2-AMINO-6-METHOXYPURINE
CBNumber:
CB0177812
???:
C6H7N5O
??? ??:
165.15
MOL ??:
20535-83-5.mol
MSDS ??:
SDS

6-Methoxyguanine ??

???
>300 °C(lit.)
?? ?
598.5±53.0 °C(Predicted)
??
1.531±0.06 g/cm3(Predicted)
?? ??
Keep in dark place,Inert atmosphere,Room temperature
???
DMSO(?? ???, ??), ?(?? ???, ??)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
9.74±0.10(Predicted)
??
????? ?? ???
BRN
645384
InChIKey
BXJHWYVXLGLDMZ-UHFFFAOYSA-N
CAS ??????
20535-83-5(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
????? 24/25
WGK ?? 3
RTECS ?? UO7473000
?? ?? ?? Irritant
HS ?? 29349990
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P501 ...? ??? / ??? ?? ???.

6-Methoxyguanine C??? ??, ??, ??

??? ??

Off-white solid

??

Antitumor agent

??

ChEBI: A methylguanine in which the methyl group is positioned on the oxygen at position 6. Formed in DNA by alkylation of the oxygen atom of guanine, most often by N-nitroso compounds and sometimes due to methylation by other compounds such as endogenous S-adenosylmethionine, it base-pairs to thymine rather than cytidine, causing a G:C to A:T transition in DNA.

?? ??

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

6-Methoxyguanine ?? ?? ? ???

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6-Methoxyguanine ?? ??

???( 237)?? ??
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6-Methoxyguanine ?? ??:

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