2-クロロニコチン酸
2-クロロニコチン酸 物理性質(zhì)
- 融點(diǎn) :
- 176-178 °C (dec.)(lit.)
- 沸點(diǎn) :
- 316.8±22.0 °C(Predicted)
- 比重(密度) :
- 1.470±0.06 g/cm3(Predicted)
- 貯蔵溫度 :
- 2-8°C
- 溶解性:
- DMSO、酢酸エチル（微量）
- 酸解離定數(shù)(Pka):
- 2.07±0.25(Predicted)
- 外見 :
- 粉
- 色:
- ホワイト～クリーム
- BRN :
- 119023
- InChI:
- InChI=1S/C6H4ClNO2/c7-5-4(6(9)10)2-1-3-8-5/h1-3H,(H,9,10)
- InChIKey:
- IBRSSZOHCGUTHI-UHFFFAOYSA-N
- SMILES:
- C1(Cl)=NC=CC=C1C(O)=O
- LogP:
- 0.988
- CAS データベース:
- 2942-59-8(CAS DataBase Reference)
- EPAの化學(xué)物質(zhì)情報(bào):
- 2-Chloronicotinic acid (2942-59-8)
| メーカー |
製品番號 |
製品説明 |
CAS番號 |
包裝 |
価格 |
更新時(shí)間 |
購入 |
|
富士フイルム和光純薬株式會(huì)社(wako)
|
W01APOOR5074 |
2-クロロニコチン酸
2-Chloronicotinic acid |
2942-59-8 |
100g |
￥4800 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式會(huì)社(wako)
|
W01APOOR5074 |
2-クロロニコチン酸
2-Chloronicotinic acid |
2942-59-8 |
500g |
￥10600 |
2024-03-01 |
購入 |
|
東京化成工業(yè)
|
C1108 |
2-クロロニコチン酸 >98.0%(HPLC)(T)
2-Chloronicotinic Acid
>98.0%(HPLC)(T) |
2942-59-8 |
25g |
￥3300 |
2024-03-01 |
購入 |
|
東京化成工業(yè)
|
C1108 |
2-クロロニコチン酸 >98.0%(HPLC)(T)
2-Chloronicotinic Acid
>98.0%(HPLC)(T) |
2942-59-8 |
250g |
￥18100 |
2024-03-01 |
購入 |
|
関東化學(xué)株式會(huì)社(KANTO)
|
07346-52 |
２‐クロロニコチン酸 >98.0%(HLC)
2‐Chloronicotinic acid >98.0%(HLC) |
2942-59-8 |
5g |
￥2100 |
2024-07-01 |
購入 |
2-クロロニコチン酸 化學(xué)特性,用途語,生産方法
外観
わずかにうすい黃色, 結(jié)晶性粉末～粉末
溶解性
エタノール及び水酸化ナトリウム溶液に溶け、水及び希塩酸にほとんど溶けない。
用途
有機(jī)合成原料、醫(yī)?農(nóng)薬中間體。
化學(xué)的特性
white to cream powder. MP>175°C (decomposition), insoluble in water, soluble in organic solvents such as benzene and toluene.
使用
2-Chloronicotinic Acid is used in the preparation of 4-thiazolidinone derivatives and Schiff bases displaying antimicrobial activity.
製造方法
Chloronicotinic acid was synthesized from nicotinic acid by oxidation by H2O2 and then chlorinationby POCl3 and PCl5 in a yield of 87.5%.
Synthesis of 2-chloronicotinic acid: Pour chlorine gas into the mixed solution of phosphorus oxychloride and phosphorus trichloride, control the temperature at about 60°C, until the remaining chlorine gas escapes, cool and add nicotinic acid N-oxide in batches, and heat the mixed solution. The reaction was carried out at 100-105°C for 1-1.5 h, and the reaction mixture was stirred for 30 min after the reaction mixture was transparent, and phosphorus oxychloride was removed under reduced pressure. The obtained residue was cooled to room temperature, and water was added to obtain the finished product of 2-chloronicotinic acid.
2-クロロニコチン酸 上流と下流の製品情報(bào)
原材料
準(zhǔn)備製品
2-クロロニコチン酸 生産企業(yè)
Global( 938)Suppliers
2-クロロニコチン酸 スペクトルデータ(1HNMR、IR1、IR2、MS、Raman)
2942-59-8(2-クロロニコチン酸)キーワード:
- 2942-59-8
- TIMTEC-BB SBB004002
- 2-chloro-3-pyridinecarboxylicaci
- 2-CHLOROPYRIDIN-3-CARBOXYLIC ACID
- 2CLNA
- 2-CHLORONICOTINIC ACID
- RARECHEM AL BO 0287
- AKOS BBS-00004231
- 2-Chloronicotinic Aicd
- 2-Chloropyridine-3-carboxylic acid, 3-Carboxy-2-chloropyridine
- 2-chlorine nicotinic acid
- 2 - chloro niacin
- 2-Chloronicoti
- 2-Chloronicotinic acid
2-Chloro-3-pyridinecarboxylic acid
- 2-Chloropyridine-3-carboxylic acid 99%
- Flunixin Related CoMpound A
- 2-CHLORO-3-CARBOXYLPYRIDINE
- 2-Chloropyridine-3-carboxylic
- 2-Chloronicotinic acid 98%
- 2-Chloro Nicotinc Acid
- 3-Pyridinecarboxylic acid, 2-chloro-
- 2-ChloroNicotinicAcid,99%-100.5%
- 2-CHLORO-3-PYRIDINECARBOXYLIC ACID / 2-CHLORONICOTINIC ACID
- 2-CHLORONICOTINIC ACID 2-CHLOROPYRIDIN-3-CARBOXYLIC ACID
- 2-CHLORONITINICACID
- 2-Chloropyridine-3-carboxylic acid,2-Chloronicotinic acid
- 2-Chloronicotinic ac
- 2-chloro-3-picolinate
- Flunixin Meglumine Impurity 1（Flunixin Meglumine EP Impurity A）
- oronicotinic acid
- Flunixin Meglumine EP Impurity A
- 2-クロロニコチン酸
- 2-クロロ-3-ピリジンカルボン酸
- 2-クロロピリジン-3-カルボン酸
- 2-クロロニコチン酸 塩化物
- ２クロロニコチン酸
- 2‐クロロニコチン酸
- クロロピリジン
- ハロピリジン
- 構(gòu)造分類