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ChemicalBook >> CAS DataBase List >>Imidazo[1,2-a]pyrazine, 5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methyl-, (5R)-

Imidazo[1,2-a]pyrazine, 5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methyl-, (5R)-

CAS No.
1609583-15-4
Chemical Name:
Imidazo[1,2-a]pyrazine, 5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methyl-, (5R)-
Synonyms
(R)-PF-06256142;Imidazo[1,2-a]pyrazine, 5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methyl-, (5R)-
CBNumber:
CB99822257
Molecular Formula:
C21H16N4O2
Molecular Weight:
356.39
MDL Number:
MOL File:
1609583-15-4.mol
Last updated:2024-10-28 23:16:16

Imidazo[1,2-a]pyrazine, 5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methyl-, (5R)- Properties

Density 1.34±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 200 mg/mL (561.20 mM; Need ultrasonic)
form Solid
pka 4.68±0.40(Predicted)
color Off-white to light yellow

Imidazo[1,2-a]pyrazine, 5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methyl-, (5R)- Chemical Properties,Uses,Production

Biological Activity

(R)-PF-06256142 is the R enantiomer of PF-06256142 with low active. PF-06256142 is a potent and selective orthosteric D1 receptor agonist that can reduce receptor desensitization relative to dopamine and other catechol-containing agonists[1].

References

[1]. Davoren JE, et al. Discovery and Lead Optimization of Atropisomer D1 Agonists with Reduced Desensitization. J Med Chem. 2018;61(24):11384-11397.

1346157-10-5
1609581-01-2
1609583-15-4
Synthesis of Imidazo[1,2-a]pyrazine, 5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methyl-, (5R)- from 5-bromo-6-methylimidazo[1,2-a]pyrazine and Furo[3,2-c]pyridine, 4-[3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]-

Imidazo[1,2-a]pyrazine, 5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methyl-, (5R)- Preparation Products And Raw materials

Imidazo[1,2-a]pyrazine, 5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methyl-, (5R)- Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19863 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088 3193328036@qq.com China 29786 68
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19699 58

View Lastest Price from Imidazo[1,2-a]pyrazine, 5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methyl-, (5R)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-PF-06256142 pictures 2024-10-28 (R)-PF-06256142
1609583-15-4
 US $1820.00-1400.00 / mg 10g TargetMol Chemicals Inc.
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  • (R)-PF-06256142
    1609583-15-4
  • US $1820.00-1400.00 / mg
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Imidazo[1,2-a]pyrazine, 5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methyl-, (5R)- (R)-PF-06256142 1609583-15-4