3-Fluoro-4-nitrobenzoic acid
- CAS No.
- 403-21-4
- Chemical Name:
- 3-Fluoro-4-nitrobenzoic acid
- Synonyms
- BUTTPARK 32\01-75;3-Fluoro-4-nitrobenzoic;uoro-4-nitrobenzoic Acid;3-FLUORO-4-NITROBENZONICACID;3-FLUORO-4-NITROBENZOIC ACID;3-FLUORO-4-NITROBENZOIC CAID;3-Fluoro-4-nitrobenzoicacid95%;3-Fluoro-4-nitrobenzoicacid99%;4-Carboxy-2-fluoronitrobenzene;3-Fluoro-4-nitrobenzoicAcid>
- CBNumber:
- CB9155507
- Molecular Formula:
- C7H4FNO4
- Molecular Weight:
- 185.11
- MDL Number:
- MFCD01862092
- MOL File:
- 403-21-4.mol
- MSDS File:
- SDS
Melting point | 174-175°C |
---|---|
Boiling point | 372.8±27.0 °C(Predicted) |
Density | 1.568±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,Room Temperature |
solubility | soluble in Methanol |
form | powder to crystal |
pka | 3.08±0.10(Predicted) |
color | White to Light yellow to Green |
InChI | InChI=1S/C7H4FNO4/c8-5-3-4(7(10)11)1-2-6(5)9(12)13/h1-3H,(H,10,11) |
InChIKey | WVZBIQSKLXJFNX-UHFFFAOYSA-N |
SMILES | C(O)(=O)C1=CC=C([N+]([O-])=O)C(F)=C1 |
CAS DataBase Reference | 403-21-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | Xi,Xn | |||||||||
Risk Statements | 36/37/38-37/38-36-22 | |||||||||
Safety Statements | 26-36/37/39-37 | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29163990 | |||||||||
NFPA 704 |
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3-Fluoro-4-nitrobenzoic acid price More Price(41)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | F0670 | 3-Fluoro-4-nitrobenzoic Acid >98.0%(GC)(T) | 403-21-4 | 5g | $34 | 2024-03-01 | Buy |
TCI Chemical | F0670 | 3-Fluoro-4-nitrobenzoic Acid >98.0%(GC)(T) | 403-21-4 | 25g | $135 | 2024-03-01 | Buy |
Alfa Aesar | H26168 | 3-Fluoro-4-nitrobenzoic acid, 98+% | 403-21-4 | 1g | $165.65 | 2024-03-01 | Buy |
Alfa Aesar | H26168 | 3-Fluoro-4-nitrobenzoic acid, 98+% | 403-21-4 | 5g | $504.65 | 2024-03-01 | Buy |
TRC | F595033 | 3-Fluoro-4-nitrobenzoic Acid | 403-21-4 | 250mg | $55 | 2021-12-16 | Buy |
3-Fluoro-4-nitrobenzoic acid Chemical Properties,Uses,Production
Uses
3-Fluoro-4-nitrobenzoic Acid is used in the synthesis of ABT-072, a non-nucleoside HCV NS5B polymerase inhibitor.
Synthesis
To a solution of 3-fluoro-4-nitrobenzyl alcohol (2.97 g) in acetone (60 ml) was added Jones reagent (13 ml), prepared from chromic acid (26.7 g) and sulfuric acid (23 ml) in water (100 ml), dropwise at 0°C. The mixture was stirred on a ice-bath for 0.5 h and quenched with isopropanol (20 ml) to be concentrated in vacuo. The residue was dissolved in ethyl acetate (30 ml) and washed with water (30 ml X 3), and brine (30 ml X 1), successively. The organic layer was dried over sodium sulfate and concentrated in vacuo to obtain a yellow solid, that was triturated with hexane. 3-fluoro-4-nitrobenzoic acid as a pale yellow solid (2.94 g, 92%).
3-Fluoro-4-nitrobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Baynoe Chem (Suzhou) Co., Ltd. | +86-512 65869404 +86-18934593683 | sales06@baynoe.com | China | 257 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18146 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29792 | 60 |
Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 810 | 58 |
Fluoropharm Co., Ltd. | +86-0571-85586753; +8613336034509 | sales@fluoropharm.com | China | 1376 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29869 | 58 |
Shanghai Arbor Chemical Co., Ltd. | 021-60451682 | act@arborchemical.com | CHINA | 904 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 18526 | 58 |
View Lastest Price from 3-Fluoro-4-nitrobenzoic acid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-11-05 | 3-Fluoro-4-nitrobenzoic acid
403-21-4
|
US $30.00-10.00 / KG | 50KG | 99% | 500000kg | Hebei Weibang Biotechnology Co., Ltd | |
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2021-07-13 | 3-Fluoro-4-nitrobenzoic acid
403-21-4
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
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2021-07-10 | 3-Fluoro-4-nitrobenzoic acid
403-21-4
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 3-Fluoro-4-nitrobenzoic acid
403-21-4
- US $30.00-10.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
-
- 3-Fluoro-4-nitrobenzoic acid
403-21-4
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 3-Fluoro-4-nitrobenzoic acid
403-21-4
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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