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ChemicalBook >> CAS DataBase List >>ASIALOGANGLIOSIDE-GM2

ASIALOGANGLIOSIDE-GM2

CAS No.
35960-33-9
Chemical Name:
ASIALOGANGLIOSIDE-GM2
Synonyms
GG3;ASIALO GM2;Glycolipid GA2;GA2 GANGLIOSIDE;Ganglioside GA2;gangliosides (Gls);Tay-Sachs globoside;CERAMIDE TRIHEXOSIDE;ASIALOGANGLIOSIDE-GM2;Glycosphingolipid GA2
CBNumber:
CB8124322
Molecular Formula:
C56H104N2O18
Molecular Weight:
1093.42756
MDL Number:
MFCD00131129
MOL File:
35960-33-9.mol
Last updated:2023-05-18 11:31:07

ASIALOGANGLIOSIDE-GM2 Properties

storage temp. −20°C
solubility Chloroform:Methanol:Water (2:1:0.1): Soluble
form lyophilized powder
FDA UNII 4UE8E5PY5V

SAFETY

Risk and Safety Statements

WGK Germany  3

ASIALOGANGLIOSIDE-GM2 price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 24629 Ganglioside GM2 Asialo Mixture ≥98% 35960-33-9 100μg $765 2024-03-01 Buy
TRC G235075 GangliosideGM2,Asialo 35960-33-9 100μg $180 2021-12-16 Buy
TRC G235075 GangliosideGM2,Asialo 35960-33-9 250μg $365 2021-12-16 Buy
Usbiological 297086 GA2-Ganglioside 35960-33-9 1mg $626 2021-12-16 Buy
AK Scientific 5309EL N-[(E,2R,3S)-1-[5-[5-[3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxyoctadec-4-en-2-yl]octadecanamide 35960-33-9 1mg $475 2021-12-16 Buy
Product number Packaging Price Buy
24629 100μg $765 Buy
G235075 100μg $180 Buy
G235075 250μg $365 Buy
297086 1mg $626 Buy
5309EL 1mg $475 Buy

ASIALOGANGLIOSIDE-GM2 Chemical Properties,Uses,Production

Description

Ganglioside GM2 asialo (asialo- GM2) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2. Asialo-GM2 levels are low-to-undetectable in normal human brain, but it accumulates in the brain of patients with Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal β-hexosaminidase A and B, respectively. It also binds to various bacteria, including Pseudomonas isolates derived from cystic fibrosis patients. Asialo-GM2 mixture contains ganglioside GM2 asialo molecular species with fatty acyl chains of variable lengths. [Matreya, LLC. Catalog No. 1512]

Uses

Ganglioside GM2, Asialo is a semisynthetic ganglioside.

General Description

Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum; contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage; for classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.

Biochem/physiol Actions

Degraded form of Asialoganglioside-GM1 ganglioside.

ASIALOGANGLIOSIDE-GM2 Preparation Products And Raw materials

ASIALOGANGLIOSIDE-GM2 Suppliers

Global( 53)Suppliers
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ganglio-n-triaosylceramide ASIALOGANGLIOSIDE GM2, FROM BOVINE BRAIN GA2 Ganglioside, Gangliotriosyl ceramide gangliosides (Gls) CERAMIDE TRIHEXOSIDE GG3 GANGLIOTRIOSYL CERAMIDE GA2 GANGLIOSIDE ASIALOGANGLIOSIDE-GM2 ASIALOGANGLIOSIDE GM2, BOVINE ASIALO GM2 Asialoganglioside GM2 Asialoganglioside-GM2 from bovine brain,GA2 Ganglioside, Gangliotriosyl ceramide Ganglioside GA2 Glycolipid GA2 Glycosphingolipid GA2 Tay-Sachs globoside Ganglioside GM2, Asialo Ganglioside GM2 Asialo Mixture 35960-33-9 Lipids Gangliosides Sphingolipids Acidic glycosphingolipids BioChemical Biochemicals and Reagents