| Identification | Back Directory | [Name]
ASIALOGANGLIOSIDE-GM2 | [CAS]
35960-33-9 | [Synonyms]
GG3
ASIALO GM2
Glycolipid GA2
Ganglioside GA2
GA2 GANGLIOSIDE
gangliosides (Gls)
Tay-Sachs globoside
CERAMIDE TRIHEXOSIDE
ASIALOGANGLIOSIDE-GM2
Glycosphingolipid GA2
Ganglioside GM2, Asialo
GANGLIOTRIOSYL CERAMIDE
ganglio-n-triaosylceramide
ASIALOGANGLIOSIDE GM2, BOVINE
Ganglioside GM2 Asialo Mixture
Asialoganglioside GM2
ASIALOGANGLIOSIDE GM2, FROM BOVINE BRAIN
GA2 Ganglioside, Gangliotriosyl ceramide
Asialoganglioside-GM2 from bovine brain,GA2 Ganglioside, Gangliotriosyl ceramide | [Molecular Formula]
C56H104N2O18 | [MDL Number]
MFCD00131129 | [MOL File]
35960-33-9.mol | [Molecular Weight]
1093.43 |
| Hazard Information | Back Directory | [Description]
Ganglioside GM2 asialo (asialo- GM2) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2. Asialo-GM2 levels are low-to-undetectable in normal human brain, but it accumulates in the brain of patients with Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal β-hexosaminidase A and B, respectively. It also binds to various bacteria, including Pseudomonas isolates derived from cystic fibrosis patients. Asialo-GM2 mixture contains ganglioside GM2 asialo molecular species with fatty acyl chains of variable lengths. [Matreya, LLC. Catalog No. 1512] | [Uses]
Ganglioside GM2, Asialo is a semisynthetic ganglioside. | [General Description]
Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum; contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage; for classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980. | [Biochem/physiol Actions]
Degraded form of Asialoganglioside-GM1 ganglioside. |
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