ChemicalBook >> CAS DataBase List >>Fidarestat
Fidarestat
- CAS No.
- 136087-85-9
- Chemical Name:
- Fidarestat
- Synonyms
- Aldos;Sk 860;CS-489;SNK-860;fidarestat;Fidarestat (SNK-860;(2S,4S)-6-Fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide;(2s,4s)-2-aminoformyl-6-fluoro-spiro[chroman-4,4'-imidazolidine]-2',5'-dione;(2S,4S)-6-Fluoro-2',5'-dioxospiro[chromane-4,4'-imidazolidine]-2-carboxamide;(2s,4s)-6-fluoro-2',5'-dioxo-2,3-dihydrospiro[chromene-4,4'-imidazolidine]-2-carboxamide
- CBNumber:
- CB5855234
- Molecular Formula:
- C12H10FN3O4
- Molecular Weight:
- 279.22
- MDL Number:
- MFCD00919183
- MOL File:
- 136087-85-9.mol
- MSDS File:
- SDS
Last updated:2024-10-28 23:16:16
| Density | 1.61±0.1 g/cm3(Predicted) |
|---|---|
| solubility | DMF: 3 mg/ml; DMSO: 5 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 1 mg/ml |
| form | A crystalline solid |
| pka | 8.46±0.40(Predicted) |
| color | White to off-white |
| FDA UNII | 8SH8T1164U |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| NFPA 704 |
|
Fidarestat price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 21756 | Fidarestat ≥98% | 136087-85-9 | 1mg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 21756 | Fidarestat ≥98% | 136087-85-9 | 5mg | $356 | 2024-03-01 | Buy |
| Cayman Chemical | 21756 | Fidarestat ≥98% | 136087-85-9 | 10mg | $632 | 2024-03-01 | Buy |
| AK Scientific | V2050 | Fidarestat | 136087-85-9 | 10mg | $802 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002700 | FIDARESTAT 95.00% | 136087-85-9 | 100MG | $2047.5 | 2021-12-16 | Buy |
Fidarestat Chemical Properties,Uses,Production
Biological Activity
Fidarestat (SNK 860) is an aldose reductase inhibitor with IC50 values of 26 nM, 33 μM and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively. Fidarestat (SNK 860) has the potential to study diabetes.
in vitro
Fidarestat (SNK-860; 1 or 4 mg/kg. po, daily for 4 weeks) reduces the concentrations of sorbitol and fructose in diabetic rats.
in vivo
Fidarestat is an inhibitor of aldose reductase, with IC 50 s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively.
target
IC50: 26 nM (Aldose reductase), 33 μM (AKR1B10), 1.8 μM (V301L AKR1B10)
Fidarestat Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 58)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29810 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15352 | 58 |
| Henan Alfa Chemical Co., Ltd | China | 11664 | 58 | ||
| Guangzhou TongYi biochemistry technology Co.,LTD | +8613073028829 | mack@tongyon.com | China | 2994 | 58 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8615195660023 | sales@senfeida.com | China | 23046 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
View Lastest Price from Fidarestat manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-28 | Fidarestat
136087-85-9
|
US $2108.00-1189.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2020-01-05 | Fidarestat
136087-85-9
|
US $1.00 / KG | 1KG | 95--99% | 1ton | Career Henan Chemical Co |
-
- Fidarestat
136087-85-9
- US $2108.00-1189.00 / mg
- TargetMol Chemicals Inc.
-
- Fidarestat
136087-85-9
- US $1.00 / KG
- 95--99%
- Career Henan Chemical Co
136087-85-9(Fidarestat)Related Search:
(2s,4s)-6-fluoro-2',5'-dioxo-2,3-dihydrospiro[chromene-4,4'-imidazolidine]-2-carboxamide
(2s,4s)-2-aminoformyl-6-fluoro-spiro[chroman-4,4'-imidazolidine]-2',5'-dione
fidarestat
(2S,4S)-6-FLUORO-2'',5''-DIOXOSPIRO(3,4-DIHYDRO-2H-1-BENZOPYRAN-4,4''-IMIDAZOLIDINE)-2-CARBOXAMIDE
(2S,4S)-2,3-Dihydro-6-fluoro-2',5'-dioxospiro[4H-1-benzopyran-4,4'-imidazolidine]-2-carboxamide
(2S,4S)-6-Fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide
SNK-860
Aldos
Sk 860
Spiro(4H-1-benzopyran-4,4'-imidazolidine)-2-carboxamide, 2,3-dihydro-2',5'-dioxo-6-fluoro-, (2S-cis)-
Spiro(4H-1-benzopyran-4,4'-imidazolidine)-2-carboxamide, 6-fluoro-2,3-dihydro-2',5'-dioxo-, (2S-cis)-
Fidarestat
(SNK-860
CS-489
Spiro[4H-1-benzopyran-4,4'-imidazolidine]-2-carboxamide, 6-fluoro-2,3-dihydro-2',5'-dioxo-, (2S,4S)-
FidarestatQ: What is
Fidarestat Q: What is the CAS Number of
Fidarestat Q: What is the storage condition of
Fidarestat Q: What are the applications of
Fidarestat
(2S,4S)-6-Fluoro-2',5'-dioxospiro[chromane-4,4'-imidazolidine]-2-carboxamide
136087-85-9