ChemicalBook >> CAS DataBase List >>ICI-118,551
ICI-118,551
- CAS No.
- 72795-19-8
- Chemical Name:
- ICI-118,551
- Synonyms
- Ici 111,581;ICI-118,551;ICI118551HCl;ICI 118,551 HYDROCHLORIDE;ICI 118551 Hydrochloride ((±ICI-118-551 HYDROCHLORIDE HIGHLY SELECTI VE B2 A;Erythro-DL-1-(7-methylindan-4-yloxy)-3-isopropylaminobutan-2-ol;erythro-DL-1-(7-Methylindan-4-yloxy)-3-isopropylamino-2-butanol;(2R,3S)-rel-1-[(2,3-Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol;2-Butanol, 1-((2,3-dihydro-7-methyl-1H-inden-4-yl)oxy)-3-((1-methylethyl)amino)-, (2R,3S)-rel-
- CBNumber:
- CB5676244
- Molecular Formula:
- C17H27NO2
- Molecular Weight:
- 277.4
- MDL Number:
- MFCD01074480
- MOL File:
- 72795-19-8.mol
Last updated:2025-01-27 09:38:02
| Melting point | 217-219°C |
|---|---|
| Boiling point | 439.3±45.0 °C(Predicted) |
| Density | 1.045±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | ethanol: 7.3 mg/mL |
| form | powder |
| pka | 13.87±0.20(Predicted) |
| color | white |
| EWG's Food Scores | 1 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
ICI-118,551 price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 5.05275 | ICI 118551 Hydrochloride - CAS 72795-19-8 - Calbiochem | 72795-19-8 | 10mg | $265 | 2024-03-01 | Buy |
| Tocris | 0821 | ICI 118,551 hydrochloride ≥98%(HPLC) | 72795-19-8 | 10 | $198 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BRS0000337 | ICI-118551 95.00% | 72795-19-8 | 5MG | $540 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | BRS0000337 | ICI-118551 95.00% | 72795-19-8 | 10MG | $575 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | MTB0000019 | ICI 118,551 HYDROCHLORIDE 95.00% | 72795-19-8 | 10MG | $702.19 | 2021-12-16 | Buy |
ICI-118,551 Chemical Properties,Uses,Production
Uses
The (R,R)-enantiomer of ICI 118551 as highly selective β2-adrenoceptor antagonist. The S,S-enantiomer is the most potent.
Definition
ChEBI: ICI 118551 is an indane substituted at position 7 by a methyl group and at position 4 by a 3-(isopropylamino)-2-hydroxybutoxy group (the 2R,3S-diastereomer). It has a role as a beta-adrenergic antagonist. It is a member of indanes, an aromatic ether, a secondary alcohol and a secondary amino compound.
Biological Activity
Primary Target
-2 adrenergic receptors', 'Reversible: yes', 'Target Ki: 1.2, 120 and 257 nM for -2, -1 and -3 receptors respectively.
ICI-118,551 Preparation Products And Raw materials
Raw materials
Preparation Products
ICI-118,551 Suppliers
Global( 59)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30231 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
| Changzhou Chenhong Biotechnology Co., Ltd. | 0519-85788828 13775037613 | sales@chemrenpharm.com | China | 3600 | 58 |
| Shanghai Botuo Biotechnology Co., LTD | 16621358918 | botuopharma888@163.com | China | 9208 | 58 |
| Chunchuang (Wuhan) Technology Co., Ltd | 15727060112 | yutianchun2007@126.com | China | 10001 | 58 |
| Cayman Chemical Company | 800-3649897 | Caymanname@qq.com | China | 21643 | 58 |
| Enzo Biochem Inc | 80-Enzo Biochem Inc. 18009420430 | info-usa@enzolifesciences.com | China | 124812 | 58 |
| Merck KGaA | (+86) 21 2033 8288 | sigmaname@qq.com | CHINA | 292394 | 58 |
| United States Biological | -- | sales@advtechind.com | United States | 6075 | 58 |
72795-19-8(ICI-118,551)Related Search:
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1of4
2-Butanol, 1-((2,3-dihydro-7-methyl-1H-inden-4-yl)oxy)-3-((1-methylethyl)amino)-, (2R,3S)-rel-
2-Butanol, 1-((2,3-dihydro-7-methyl-1H-inden-4-yl)oxy)-3-((1-methylethyl)amino)-, (R*,S*)-(+-)-
Erythro-DL-1-(7-methylindan-4-yloxy)-3-isopropylaminobutan-2-ol
Ici 111,581
(2R,3S)-rel-1-[(2,3-Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol
(+/-)-1-[2,3-(DIHYDRO-7-METHYL-1H-INDEN-4-YL)OXY]-3-[(1-METHYLETHYL)AMINO]-2-BUTANOL HYDROCHLORIDE
ICI-118-551 HYDROCHLORIDE HIGHLY SELECTI VE B2 A
ICI118551HCl
ICI-118,551
ICI 118,551 HYDROCHLORIDE
ICI 118551 Hydrochloride ((±
erythro-DL-1-(7-Methylindan-4-yloxy)-3-isopropylamino-2-butanol
72795-19-8
C17H28NO2Cl