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ChemicalBook >> CAS DataBase List >>1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL

1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL

CAS No.
488-41-5
Chemical Name:
1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL
Synonyms
r54;myebrol;nsc-94100;NSC 94110;mieobromol;nci-c04762;dibromannit;myelobromol;Mielobromol;mitobronitol
CBNumber:
CB3692682
Molecular Formula:
C6H12Br2O4
Molecular Weight:
307.97
MDL Number:
MFCD00045046
MOL File:
488-41-5.mol
MSDS File:
SDS
Last updated:2024-12-18 14:08:52

1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL Properties

Melting point 176-178°
Boiling point 511.2±50.0 °C(Predicted)
Density 1.8987 (rough estimate)
refractive index 1.4840 (estimate)
storage temp. −20°C
pka 12.61±0.20(Predicted)
FDA UNII 5UP30YED7N
ATC code L01AX01
EPA Substance Registry System Mitobronitol (488-41-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS08,GHS07
Signal word  Danger
Hazard statements  H302-H350
Precautionary statements  P264-P270-P301+P312-P330-P501
Hazard Codes  T
Risk Statements  45-22
Safety Statements  53-22-36/37/39-45
WGK Germany  3
RTECS  OP2800000

1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation CRB0005708 1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL 95.00% 488-41-5 5MG $502.46 2021-12-16 Buy
AHH MT-08038 1,6-Dibromo-1,6-dideoxy-D-mannitol 98% 488-41-5 1g $355 2021-12-16 Buy
Product number Packaging Price Buy
CRB0005708 5MG $502.46 Buy
MT-08038 1g $355 Buy

1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL Chemical Properties,Uses,Production

Originator

Myelobromol,Hormonchemie,W. Germany,1967

Uses

Antineoplastic.

Definition

ChEBI: Mitobronitol is an alcohol and an organobromine compound.

Manufacturing Process

750 g D-mannitol are dissolved in 4,000 ml of a 48% aqueous hydrogenbromide solution, whereupon the solution thus obtained is saturated at 0°Cwith gaseous hydrogen bromide until a HBr content of 69 to 70% is achieved.The reaction mixture is heated for 6 hours at 60°C in an autoclave, is thendecolorized with charcoal, extracted with 1 liter chloroform twice and dilutedwith 7 liters of water. The pH value of the solution is adjusted by means ofsodium bicarbonate to1 to 2. The crystals precipitated after cooling for a dayare filtered and washed with water until free from acid. 250 g crude 1,6-dibromo-1,6-didesoxy-D-mannitol are obtained. MP 176° to 178°C. Analysis:Br % = 52 (calc.: 51.9).
250 g of the crude DBM are dissolved in 2.5 liters of hot methanol and ondecolorizing and filtration 2.5 liters of dichloroethane are added. 220 g ofcrystalline DBM are obtained. MP 178°C. Br % = 51.9.

Therapeutic Function

Cancer chemotherapy

General Description

White powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

A halogenated alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.

Fire Hazard

Flash point data for 1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL are not available, but 1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL is probably combustible.

1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 44)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
TopScience Biochemical 		00852-68527855 info@itopbiochem.com China Hong Kong 902 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 22787 58
Finetech Industry Limited 		+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9639 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 5221 58
Watson Biotechnology Co.,Ltd 		+86-18186686046 +86-18186686046 sales01@watsonbiotech.cn China 5841 58
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19885 58
Olix (Shanghai) Pharmaceutical Technology Co., Ltd 17316404525 209533805@qq.com China 9903 58

View Lastest Price from 1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Mitobronitol pictures 2024-10-28 Mitobronitol
488-41-5
 US $1980.00-1520.00 / mg 10g TargetMol Chemicals Inc.
1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL USP/EP/BP pictures 2021-07-06 1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL USP/EP/BP
488-41-5
 US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
  • Mitobronitol pictures
  • Mitobronitol
    488-41-5
  • US $1980.00-1520.00 / mg
  • TargetMol Chemicals Inc.
1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL 1,6-dibrom-1,6-didesoxy-d-mannit 1,6-dibromo-1,6-d-didesoxymannitol 1,6-dibromomannitol 6-dibromo-1,6-dideoxy-d-mannito d-dibromomannitol dibromannit dibromomannitol mieobromol mitobronitol myebrol myelobromol nci-c04762 nsc-94100 r54 Dibrommannit D-Mannitol, 1,6-dibromo-1,6-dideoxy- 1,6-Dibromo-1,6-dideoxymannitol 1,6-Dibromo-D-mannitol 1,6-Dideoxy-1,6-dibromo-D-mannitol Dibromannitol D-Mannitol, 1,6-dibromo-1,6-dideoxy- (9CI) Mannitol, 1,6-dibromo-1,6-dideoxy-, D- (8CI) Mielobromol NSC 94110 MANNITOL,1,6-DIBROMO-1,6-DIDEOXY-,D- (2S,3S,4S,5S)-1,6-dibromohexane-2,3,4,5-tetrol (2S,3S,4S,5S)-1,6-Dibromohexane-2,3,4,5-tetraol 1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL USP/EP/BP 488-41-5 C6H12Br2O4 Monosaccharide BioChemical Biochemicals and Reagents Carbohydrates Monosaccharide Carbohydrates D-FBiochemicals and Reagents Carbohydrates A to Carbohydrates