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ChemicalBook >> CAS DataBase List >>BI605906

BI605906

CAS No.
960293-88-3
Chemical Name:
BI605906
Synonyms
CS-2032;BI605906;BI-605906,BI605906;3-AMino-4-(1,1-difluoropropyl)-6-(4-Methylsulfonylpiperidin-1-yl)thieno[2,3-b]pyridine-2-carboxaMide;3-amino-4-(1,1-difluoropropyl)-6-(4-methanesulfonylpiperidin-1-yl)thieno[2,3-b]pyridine-2-carboxamide;3-Amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]thieno[2,3-b]pyridine-2-carboxamide;Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]-
CBNumber:
CB12627596
Molecular Formula:
C17H22F2N4O3S2
Molecular Weight:
432.51
MDL Number:
MFCD22665698
MOL File:
960293-88-3.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02

BI605906 Properties

Boiling point 713.7±60.0 °C(Predicted)
Density 1.48±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Acetonitrile: 1 mg/ml; DMSO: 30 mg/ml
form A crystalline solid
pka 16.18±0.30(Predicted)
color Light yellow to yellow
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

BI605906 price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML3370 BI605906 ≥98% (HPLC) 960293-88-3 5MG $92.8 2023-06-20 Buy
Sigma-Aldrich SML3370 BI605906 ≥98% (HPLC) 960293-88-3 25MG $375 2023-06-20 Buy
Cayman Chemical 19184 BI-605906 ≥98% 960293-88-3 1mg $76 2024-03-01 Buy
Cayman Chemical 19184 BI-605906 ≥98% 960293-88-3 5mg $190 2024-03-01 Buy
Cayman Chemical 19184 BI-605906 ≥98% 960293-88-3 10mg $317 2024-03-01 Buy
Product number Packaging Price Buy
SML3370 5MG $92.8 Buy
SML3370 25MG $375 Buy
19184 1mg $76 Buy
19184 5mg $190 Buy
19184 10mg $317 Buy

BI605906 Chemical Properties,Uses,Production

Uses

BI 605906, is a novel inhibitors of the kappa B kinase subunit β (IKKβ; IC50 = 380 nM).

Biological Activity

BI605906 is a selective, ATP-competitive IKB kinase β (IKK2, IKKβ, IKK-beta) inhibitor (IC50 = 380 nM, [ATP] = 0.1 mM) with no potency toward 100 other kinases, including IKKα, IKKε, TBK1, and IGF1R (IC50 ≥7.6 μM). BI605906 (10 μM) effectively blocks IKK-β-dependent phosphorylation of IKKε and TBK1 in IKKα-/- MEFs upon IL-1α (5 ng/mL) induction.

storage

Store at -20°C

BI605906 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 55)Suppliers
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ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33025 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32159 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43340 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+86-18621343501; +undefined18621343501 product@acmec-e.com China 33338 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
SHANGHAI KEAN TECHNOLOGY CO., LTD. 		+8613817748580 cooperation@kean-chem.com China 40066 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2922 55
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 12952 65
BI605906 3-AMino-4-(1,1-difluoropropyl)-6-(4-Methylsulfonylpiperidin-1-yl)thieno[2,3-b]pyridine-2-carboxaMide 3-Amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]thieno[2,3-b]pyridine-2-carboxamide CS-2032 Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]- BI-605906,BI605906 3-amino-4-(1,1-difluoropropyl)-6-(4-methanesulfonylpiperidin-1-yl)thieno[2,3-b]pyridine-2-carboxamide 960293-88-3 C17H22F2N4O3S2 Inhibitor