ChemicalBook >> CAS DataBase List >>BI605906
BI605906
- CAS No.
- 960293-88-3
- Chemical Name:
- BI605906
- Synonyms
- CS-2032;BI605906;BI-605906,BI605906;3-AMino-4-(1,1-difluoropropyl)-6-(4-Methylsulfonylpiperidin-1-yl)thieno[2,3-b]pyridine-2-carboxaMide;3-amino-4-(1,1-difluoropropyl)-6-(4-methanesulfonylpiperidin-1-yl)thieno[2,3-b]pyridine-2-carboxamide;3-Amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]thieno[2,3-b]pyridine-2-carboxamide;Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]-
- CBNumber:
- CB12627596
- Molecular Formula:
- C17H22F2N4O3S2
- Molecular Weight:
- 432.51
- MDL Number:
- MFCD22665698
- MOL File:
- 960293-88-3.mol
- MSDS File:
- SDS
Last updated:2025-01-27 09:38:02
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
BI605906 price More Price(15)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML3370 | BI605906 ≥98% (HPLC) | 960293-88-3 | 5MG | $92.8 | 2023-06-20 | Buy |
Sigma-Aldrich | SML3370 | BI605906 ≥98% (HPLC) | 960293-88-3 | 25MG | $375 | 2023-06-20 | Buy |
Cayman Chemical | 19184 | BI-605906 ≥98% | 960293-88-3 | 1mg | $76 | 2024-03-01 | Buy |
Cayman Chemical | 19184 | BI-605906 ≥98% | 960293-88-3 | 5mg | $190 | 2024-03-01 | Buy |
Cayman Chemical | 19184 | BI-605906 ≥98% | 960293-88-3 | 10mg | $317 | 2024-03-01 | Buy |
BI605906 Chemical Properties,Uses,Production
Uses
BI 605906, is a novel inhibitors of the kappa B kinase subunit β (IKKβ; IC50 = 380 nM).
Biological Activity
BI605906 is a selective, ATP-competitive IKB kinase β (IKK2, IKKβ, IKK-beta) inhibitor (IC50 = 380 nM, [ATP] = 0.1 mM) with no potency toward 100 other kinases, including IKKα, IKKε, TBK1, and IGF1R (IC50 ≥7.6 μM). BI605906 (10 μM) effectively blocks IKK-β-dependent phosphorylation of IKKε and TBK1 in IKKα-/- MEFs upon IL-1α (5 ng/mL) induction.
storage
Store at -20°C
BI605906 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 55)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33025 | 60 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2922 | 55 | |
BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 12952 | 65 |
BI605906
3-AMino-4-(1,1-difluoropropyl)-6-(4-Methylsulfonylpiperidin-1-yl)thieno[2,3-b]pyridine-2-carboxaMide
3-Amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]thieno[2,3-b]pyridine-2-carboxamide
CS-2032
Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]-
BI-605906,BI605906
3-amino-4-(1,1-difluoropropyl)-6-(4-methanesulfonylpiperidin-1-yl)thieno[2,3-b]pyridine-2-carboxamide
960293-88-3
C17H22F2N4O3S2
Inhibitor