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4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT

4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT Struktur
153436-22-7
CAS-Nr.
153436-22-7
Englisch Name:
4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT
Synonyma:
GAVESTINEL;1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propen-1-yl]-;4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT;4,6-Dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl)-1-propenyl]-1H-indole-2-carboxylic acid sodium salt
CBNumber:
CB9845365
Summenformel:
C18H12Cl2N2O3
Molgewicht:
375.21
MOL-Datei:
153436-22-7.mol

4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT Eigenschaften

Schmelzpunkt:
>270°C (dec.)
Siedepunkt:
701.1±60.0 °C(Predicted)
Dichte
1.561±0.06 g/cm3(Predicted)
storage temp. 
Desiccate at RT
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
pka
3.77±0.30(Predicted)
Aggregatzustand
Solid
Farbe
Pale Yellow
Stabilit?t:
Hygroscopic

Sicherheit

4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Treatment of stroke (N-methylD-aspartate NMDA receptor antagonist).

Biologische Aktivit?t

Highly potent and selective non-competitive antagonist acting at the strychnine-insensitive glycine binding site of the NMDA receptor-channel complex (K d = 0.8 nM). Displays > 1000-fold selectivity over NMDA, AMPA and kainate binding sites. Orally bioavailable and active in vivo .

Sicherheitsprofil

A poison by intravenous route. When heated to decomposition it emits toxic vapors of NOx and Cl-.

4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 9)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266
 China 4574 55
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Suzhou Chenrui Biotechnology Co. LTD 17625585511
 1580084073@qq.com China 673 58

153436-22-7()Verwandte Suche:

  • GAVESTINEL
  • 4,6-Dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl)-1-propenyl]-1H-indole-2-carboxylic acid sodium salt
  • 4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT
  • 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propen-1-yl]-
  • 153436-22-7
  • C18H12Cl2N2O3
  • C18H11Cl2N2O3Na
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